Grape

Also known as: European Grape, Wine Grape, Grapevine, Vigne Vinifere (Fr.), Weinrebe (Ger.), Parra (Sp.), Vid (Sp.)

Botanical Overview

Grape (Vitis vinifera) is a flowering plant in the Vitaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. This species belongs to the Vitaceae family, a group of flowering plants.

General Description

As of 2012, there were between 5,000 and 10,000 varieties of Vitis vinifera grapes though only a few are of commercial significance for wine and table grape production.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Vitaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Grape has been recorded in 10 countries and territories worldwide, including Afghanistan, Switzerland, Germany, Spain, France, and others.

Traditional Uses

Grape has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.

Digestive health.

  • Diarrhea
  • Laxative
  • Stomachic

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Expectorant

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Skin

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Phenolic: antioxidant compounds that neutralize free radicals
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Afghanistan, Switzerland, Germany, Spain, France, United Kingdom, Greece, Italy, Portugal, United States.

Complete Use Records

CategoryCultural Context
DiarrheaElsewhere, Haiti, Turkey
DiureticChina, Elsewhere, Turkey
IntoxicantSpain, Turkey, US
RefrigerantChina, Elsewhere, Turkey
CancerEurope, Lithuania
TuberculosisIraq, Turkey
DemulcentElsewhere, Turkey
LaxativeElsewhere, Turkey
StomachicElsewhere, Iraq
WartItaly, US(PA)
AstringentElsewhere, Turkey
ApertifUS
CachexiaIraq
ExpectorantElsewhere
HoarsenessIraq
LiqueurUS
Preventitive(Hunger)China
RestorativeTurkey
SeasicknessEurope
Sore(Throat)Kurdistan
ThroatElsewhere
IntellectChina
SkinElsewhere
TonicTurkey
HemostatTurkey
OphthalmiaElsewhere

Complete Chemical Inventory

CompoundFormulaMW
(+)-CATECHINC₁₅H₁₄O₆290.27 Da
(+)-GALLOCATECHINC₁₅H₁₄O₇306.27 Da
(-)-EPICATECHINC₁₅H₁₄O₆290.27 Da
(-)-EPICATECHIN-3-GALLATEC₂₂H₁₈O₁₀442.4 Da
(-)-EPIGALLOCATECHINC₁₅H₁₄O₇306.27 Da
(-)-GALLOCATECHINC₁₅H₁₄O₇306.27 Da
(DL)-GALLOCATECHIN
16-BETA-HYDROXY-3-OXO-OLEAN-1-12-DIEN-28-OIC-ACID
16-BETA-HYDROXY-3-OXO-OLEAN-12-EN-28-OIC-ACID
2,2,6-TRIMETHYL-8-(1-HYDROXY-ETHYL)-7-OXA-BICYCLO-(4,3,0)-NONA-4,9-DIENE
2,6-DIMETHYL-TRANS,TRANS-OCTA-2,6-DIEN-1,8-DIOL
2,6-DIMETHYL-TRANS-OCTA-2,7-DIEN-1,6-DIOL-6-O-ALPHA-D-ARABINOFURANOSYL-BETA-D-BETA-D-GLUCOPYRANOSIDE
2,6-DIMETHYL-TRANS-OCTA-2,7-DIEN-1,6-DIOL-BETA-D-GLUCOPYRANOSIDE
2-METHOXY-3-ISOBUTYL-PYRAZINE
2-PHENYLETHAN-1-OLC₈H₁₀O122.16 Da
2-PHENYLETHAN-2-OL-6-BETA-D-APIOFURANOSYL-BETA-D-GLUCOSIDE
2-PHENYLETHYL-AMINEC₈H₁₁N121.18 Da
2-TRANS-4-CIS-DECADIENAL
2-TRANS-DECENAL
2-TRANS-HEPTANAL
24-METHYL-CYCLOARTENOL
3,7-DIMETHYL-OCT-1-ENE-3,6,7-TRIOL
3,7-DIMETHYL-OCT-1-ENE-3,7-DIOL
3,7-DIMETHYL-OCTA-1,5,7-TRIEN-3-OLC₁₀H₁₆O152.23 Da
3,7-DIMETHYL-OCTA-1,5-DIEN-3,7-DIOL
3,7-DIMETHYL-OCTA-1,6-DIEN-3,5-DIOL
3,7-DIMETHYL-OCTA-1,7-DIEN-3,6-DIOLC₁₀H₁₈O₂170.25 Da
3-BETA-29-DIHYDROXY-OLEAN-12-EN-28-OIC-ACID
3-BETA-HYDROXY-OLEAN-12-EN-28-ALDEHYDE
3-HYDROXY-BETA-DAMASCONEC₁₃H₂₀O₂208.30 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources