Periwinkle

Also known as: Running-Myrtle

Botanical Overview

Periwinkle (Vinca minor) is a flowering plant in the Apocynaceae family. This plant has earned a place in traditional medicine through its consistent therapeutic benefits, recorded across multiple cultures. The dogbane family (Apocynaceae) includes herbs, shrubs, vines, and trees with milky sap containing alkaloids and cardiac glycosides. The flowers are typically five-petaled and often showy with a tubular corolla. Many species in this family are highly toxic but also source of important cardiac medications.

General Description

Other vernacular names used in cultivation include small periwinkle, common periwinkle, and sometimes in the United States, myrtle or creeping myrtle.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Apocynaceae family is primarily tropical and subtropical. Notable medicinal members include:

Geographic Distribution

Periwinkle has been recorded in 10 countries and territories worldwide, including Austria, Belgium, Switzerland, Czech Republic, Germany, and others.

Traditional Uses

Periwinkle has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.

Digestive health.

  • Carminative
  • Diarrhea
  • Dysentery

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Catarrh

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Eczema
  • Skin

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Emetic. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Austria, Belgium, Switzerland, Czech Republic, Germany, France, United Kingdom, Netherlands, Sweden, United States.

Complete Use Records

CategoryCultural Context
DepurativeEurasia, Europe, Turkey
HemostatEurasia, Europe, Turkey
AstringentElsewhere, Turkey
HypertensionElsewhere, Europe
TonicElsewhere, Turkey
DiureticEurope, Turkey
BactericideElsewhere
CarminativeEurope
DiarrheaElsewhere
DysenteryElsewhere
EczemaEurasia
EmeticEurope
LactogogueTurkey
MenorrhagiaElsewhere
PhthisisElsewhere
ScalpElsewhere
ScurvyEurope
SkinElsewhere
SpasmolyticElsewhere
TeaElsewhere
CollyriumElsewhere
PilesElsewhere
SedativeElsewhere
LactifugeSpain
CatarrhEurasia
HomeopathyEurasia
Tumor(Uvula)

Complete Chemical Inventory

CompoundFormulaMW
(+)-ISO-EBURNAMINE
(+)-QUEBRACHAMINEC₁₉H₂₆N₂282.4 Da
(-)-1-NORVINCORINE
(-)-16-METHOXY-20-OXO-VINCADIFFORMINE
(-)-EBURNAMENINEC₁₉H₂₂N₂278.4 Da
(-)-EBURNAMINEC₁₉H₂₄N₂O296.4 Da
(-)-EBURNAMONINEC₁₉H₂₂N₂O294.4 Da
(-)-MINOVINCINEC₂₁H₂₄N₂O₃352.4 Da
(-)-VINCADIFFORMINEC₂₁H₂₆N₂O₂338.4 Da
(DL)-EBURNAMONINE
(DL)-VINCADIFFORMINE
1,2-DEHYDROASPIDOSPERMIDINE
10-METHOXY-DEACETYLAKUAMMILINE
10-METHOXY-VELLOSIMINE
10-METHOXY-VINCAMIDINE
11-12-DIMETHOXY-EBURNAMONINE
11-METHOXY-EBURNAMONINE
11-METHOXY-MINOVINCINE
11-METHOXY-MINOVINCININE
11-METHOXY-VINCADIFFORMINE
11-METHOXYVINCAMINE
14-EPIVINCAMINEC₂₁H₂₆N₂O₃354.4 Da
16-EPIVINCAMINEC₂₁H₂₆N₂O₃354.4 Da
16-METHOXY-20-OXO-1-VINCADIFFORMINE
16-METHOXYMINOVINCININEC₂₂H₂₈N₂O₄384.5 Da
2-BETA-16-BETA-DIHYDROAKKUAMICINE
2-CARBOXYARABINITOLC₆H₁₂O₇196.16 Da
20-HYDROXYVINCAMINE
3-BETA-GLUCOSYLOXY-2-HYDROXYBENZOIC-ACID
4-METHYL-AKUAMMICINIUM-CHLORIDE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources