Vancouveria hexandra

Botanical Overview

Vancouveria hexandra is a species in the Berberidaceae family. The barberry family (Berberidaceae) includes shrubs and herbs with alternate or basal leaves and yellow wood or roots due to alkaloid content. The flowers have six sepals and six petals arranged in whorls, and the fruits are berries or capsules. Many species produce isoquinoline alkaloids like berberine with antimicrobial activity. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 24 compounds in this species, suggesting potential medicinal value.

Family Context

The Berberidaceae family is widely distributed in temperate regions. Notable medicinal members include:

Geographic Distribution

Vancouveria hexandra has been recorded in 10 countries and territories worldwide, including Canada, Colombia, Czech Republic, Germany, Denmark, and others.

Active Compounds

Phytochemical research has identified 24 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Canada, Colombia, Czech Republic, Germany, Denmark, United Kingdom, Norway, New Zealand, United States, Unknown.

Complete Chemical Inventory

CompoundFormulaMW
2-(P-HYDROXY-PHENOXY)-5-HYDROXY-7-METHOXY-BENZOCHROMONE
3-(6-O-ACETYL-GALACTOSYL-(1,3)-RHAMNOSIDE)-7-GLUCOSIDE-ANHYDROICARITIN
3-GALACTOSYL-(1,3)-RHAMNOSIDE-7-GLUCOSIDE-ANHYDROICARITIN
3-O-FUCOSYL-RHAMNOSIDE-ANHYDROICARITIN
3-O-GLUCOSYL-7-O-GLUCOSIDE-ANHYDROICARITIN
4',5,7-TRIHYDROXY-3'-(2-HYDROXY-3-METHYL-BUT-4-ENYL)-FLAVONE
4',5,7-TRIHYDROXY-3'-6-DI-(2-HYDROXY-3-METHYL-BUT-4-ENYL)-FLAVONE
AFZELINC₂₁H₂₀O₁₀432.4 Da
EPIMEDIN-AC₄₀H₅₂O₁₉836.8 Da
EPIMEDIN-BC₃₈H₄₈O₁₉808.8 Da
EPIMEDIN-CC₃₉H₅₀O₁₉822.8 Da
EPIMEDOSIDE-AC₃₂H₃₈O₁₅662.6 Da
EPIMEDOSIDE-EC₃₇H₄₆O₁₉794.7 Da
HEXANDRASIDE-AC₃₉H₅₀O₂₀838.8 Da
HEXANDRASIDE-BC₄₁H₅₂O₂₁880.8 Da
HEXANDRASIDE-CC₄₃H₅₆O₂₄956.9 Da
HEXANDRASIDE-DC₃₉H₅₀O₁₉822.8 Da
HEXANDRASIDE-EC₃₂H₃₈O₁₆678.6 Da
HEXANDRASIDE-FC₃₉H₅₀O₂₀838.8 Da
ICARIINC₃₃H₄₀O₁₅676.7 Da
IKARISOSIDE-CC₃₉H₅₀O₁₉822.8 Da
IKARISOSIDE-FC₃₁H₃₆O₁₄632.6 Da
KAEMPFERITRINC₂₇H₃₀O₁₄578.5 Da
KAEMPFEROL-3-O-GLUCOSYL-RHAMNOSIDE-7-O-RHAMNOSIDE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources