European Nettle

Also known as: Stinging Nettle

Botanical Overview

Commonly known as European Nettle, this species belongs to the Urticaceae family. Traditional healers across continents have independently recognized the medicinal value of this species, leading to one of the most extensive ethnobotanical records available. This species belongs to the Urticaceae family, a group of flowering plants.

General Description

Originally native to Europe, much of temperate Asia and western North Africa, it is now found worldwide. The species is divided into six subspecies, five of which have many hollow stinging hairs called trichomes on the leaves and stems, which act like hypodermic needles, injecting histamine and other chemicals that produce a stinging sensation upon contact (“contact urticaria”, a form of contact dermatitis). The plant has a long history of use as a source for traditional medicine, food, tea, and textile raw material in ancient (such as Saxon) and modern societies.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Urticaceae family is widely distributed. Notable medicinal members include:

  • Ramie — 20 documented uses

Traditional Uses

European Nettle has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.

Digestive health.

  • Vermifuge

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Asthma
  • Bronchitis
  • Catarrh

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Burn

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Complete Use Records

CategoryCultural Context
RheumatismCanada(Nootka), Europe, India, Turkey, US(Flathead)
DepurativeElsewhere, Europe, Turkey, UK
DiureticElsewhere, Europe, Turkey
AlopeciaCanada(Kwakiutl), Europe
AnodyneCanada(Kwakiutl), India
CounterirritantCanada(Nootka), India
GoutEurope, India
ParalysisElsewhere, Iraq
VermifugeElsewhere, Turkey
AcheCanada(Nootka)
Ache(Back)US(Flathead)
AsthmaTurkey
Ataxia(Locomotor)Canada(Kwakiutl)
BloodTurkey
BronchitisTurkey
BruiseCanada(Nootka)
BurnEurope
CatarrhElsewhere
ChestCanada(Kwakiutl)
CholecystitisUSSR
ConstipationUSSR
CosmeticEurope
DandruffElsewhere
DropsyEurope
EpilepsyUS(Flathead)
EpistaxisIraq
Evil eyeIndia
HematemesisKurdistan
HematoptysisElsewhere
HemorrhageElsewhere

Complete Chemical Inventory

CompoundFormulaMW
(+)-ISOLARICIRESINOLC₂₀H₂₄O₆360.4 Da
(+)-NEOOLIVILC₂₀H₂₄O₇376.4 Da
(-)-3,4-DIVANILLYLTETRAHYDROFURANC₂₀H₂₄O₅344.4 Da
(-)-PINORESINOLC₂₀H₂₂O₆358.4 Da
(-)-SECOISOLARICIRESINOLC₂₀H₂₆O₆362.4 Da
(10E,12Z)-9-HYDROXY-10,12-OCTADECADIENOIC-ACID
(6'PALMITOYL)-BETA-SITOSTEROL-3-O-BETA-GLUCOSIDE
13-HYDROXYOCTADECA-CIS-9-TRANS-11-DIENOIC-ACID
2-METHYLHEPTEN-(2)-ON-(6)
24R-ETHYL-5-ALPHA-CHOLESTANE-3-BETA,6-ALPHA-DIOL
4-HYDROXY-3-METHOXYPHENYLPROPANE
5-HYDROXYTRYPTAMINEC₁₀H₁₂N₂O176.21 Da
7'(E)-4,4',7,9,9'-PENTAHYDROXY-3,3'-DIMETHOXY-8.O,4'-LIGNAN
7'(E)-7-O-BETA-D-GLUCOPYRANOSYL-4,4',7,9,9'PENTAHYDROXY-3,3'-DIMETHOXY-8-O,4'-LIGNAN
7-ALPHA-HYDROXY-SITOSTEROL
7-ALPHA-HYDROXYDAUCOSTEROL
7-ALPHA-HYDROXYSITOSTEROL-3-O-BETA-D-GLUCOSIDE
7-BETA-HYDROXYDAUCOSTEROL
7-BETA-HYDROXYSITOSTEROL
7-BETA-HYDROXYSITOSTEROL-3-O-BETA-D-GLUCOSIDE
9'-ACETYL-GLUCOSIDE
9,10,13-TRIHYDROXYOCTADEC-TRANS-11-ENOIC-ACID
9,12,13-TRIHYDROXY-OCTADEC-TRANS-10-ENOIC-ACID
9,9'-BIACETYL-NEOOLIVIL
9,9'-BIACETYL-NEOOLIVIL-GLUCOSIDE
9,9'-BISACETYL-NEOOLIVIL
9-ACETYL-NEOOLIVIL
9-ACETYL-NEOOLIVIL-4-O-BETA-D-GLUCOSIDE
ACETIC-ACIDC₂H₄O₂60.05 Da
ACETOPHENONEC₈H₈O120.15 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources