Cat's Claw

Also known as: Garabato Amarillo, Una de Gato

Botanical Overview

Cat’s Claw (Uncaria tomentosa) is a species in the Pedaliaceae family. This species belongs to the Pedaliaceae family, a group of flowering plants. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 30 compounds in this species, suggesting potential medicinal value.

General Description

It is known as cat’s claw or uña de gato in Spanish because of its claw-shaped thorns. The plant root bark is used in herbalism for a variety of ailments, and is sold as a dietary supplement. There is no high-quality clinical evidence that it has any benefit for treating human diseases.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Pedaliaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Cat’s Claw has been recorded in 10 countries and territories worldwide, including Bolivia, Brazil, Belize, Colombia, Costa Rica, and others.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Phenolic: antioxidant compounds that neutralize free radicals
  • Sterol: cholesterol-like compounds with anti-inflammatory properties

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Additional phytochemical investigation could identify novel bioactive compounds in this plant.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Bolivia, Brazil, Belize, Colombia, Costa Rica, Ecuador, Nicaragua, Panama, Peru, Venezuela.

Complete Chemical Inventory

CompoundFormulaMW
(-)-EPICATECHINC₁₅H₁₄O₆290.27 Da
16-ALPHA-HYDROXY-3-BETA-METHOXY-URSA-12,19(29)-DIEN-27,28-DIOIC-ACID
27-O-BETA-D-GLUCOPYRANOSIDE-QUINOVIC-ACID
3-BETA-6-BETA-19-ALPHA-TRIHYDROXY-23-OXO-URS-12-EN-28-OIC ACID
3-BETA-6-BETA-19-ALPHA-TRIHYDROXY-URS-12-ENE-23-28-DIOIC ACID
3-BETA-HYDROXY-3-OXO-URS-12-EN-27,28-DIOIC-ACID
3BETA,6BETA,19ALPHA-TRIHYDROXY-URS-12-EN-28-OIC-ACID
5ALPHA-CARBOXYSTRICTOSIDINEC₂₈H₃₄N₂O₁₁574.6 Da
6-BETA-19-ALPHA-DIHYDROXY-3-OXO-URS-12-EN-28-OIC-ACID
AKUAMMIGINEC₂₁H₂₄N₂O₃352.4 Da
ALLOISOPTEROPODINE
ALLOPTEROPODINE
ANGUSTINEC₂₀H₁₅N₃O313.4 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CAMPESTEROLC₂₈H₄₈O400.7 Da
CHLOROGENIC-ACIDC₁₆H₁₈O₉354.31 Da
CINCHONAIN-1-A
CINCHONAIN-1-B
CORYNOXEINEC₂₂H₂₆N₂O₄382.5 Da
DIHYDROCORYNANTHEINEC₂₂H₂₈N₂O₃368.5 Da
DIHYDROCORYNANTHEINE-N-OXIDE
HIRSUTEINEC₂₂H₂₆N₂O₃366.5 Da
HIRSUTINEC₂₂H₂₈N₂O₃368.5 Da
HIRSUTINE-N-OXIDEC₂₂H₂₈N₂O₄384.5 Da
ISOAJMALICINEC₂₁H₂₄N₂O₃352.4 Da
ISOCORYNOXEINEC₂₂H₂₆N₂O₄382.5 Da
ISOMITRAPHYLLINEC₂₁H₂₄N₂O₄368.4 Da
ISOPTEROPODINEC₂₁H₂₄N₂O₄368.4 Da
ISORHYNCHOPHYLLINEC₂₂H₂₈N₂O₄384.5 Da
ISORHYNCHOPHYLLINE-N-OXIDEC₂₂H₂₈N₂O₅400.5 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources