Cat's Claw

Also known as: Una de Gato, Garabato Colorado, Tambor Huasca, Ungunagi

Botanical Overview

Cat’s Claw (Uncaria guianensis) belongs to the Pedaliaceae family. Limited but reliable traditional records indicate this plant has recognized medicinal applications in one or more healing traditions. This species belongs to the Pedaliaceae family, a group of flowering plants.

General Description

Other names for the plant include uña de gato, Paraguayo and vincaria. Uncaria guianensis contains many phytochemicals ((-)-epicatechin, alkaloid, beta-Sitosterol, campesterol, campherol, catechol, catechutannic acid, chlorogenic acid, ellagic acid, gallic acid, hyperin, oleanolic acid, rutin, stigmasterol, ursolic acid) and proanthocyanidin B1 and proanthocyanidin B2, B type proanthocyanidins, in the root.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Pedaliaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Cat’s Claw has been recorded in 10 countries and territories worldwide, including Bolivia, Brazil, Colombia, Ecuador, French Guiana, and others.

Traditional Uses

Cat’s Claw has been traditionally used for digestive health.

Digestive health.

  • Dysentery

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Phenolic: antioxidant compounds that neutralize free radicals
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Bolivia, Brazil, Colombia, Ecuador, French Guiana, Guyana, Peru, Suriname, Venezuela, Unknown.

Complete Use Records

CategoryCultural Context
DysenteryGuiana

Complete Chemical Inventory

CompoundFormulaMW
ALKALOIDS
ANGUSTINEC₂₀H₁₅N₃O313.4 Da
ANGUSTOLINEC₂₀H₁₇N₃O₂331.4 Da
CHLOROGENIC-ACIDC₁₆H₁₈O₉354.31 Da
DIHYDROCORYNANTHEINEC₂₂H₂₈N₂O₃368.5 Da
DIHYDROKAEMPFEROLC₁₅H₁₂O₆288.25 Da
EPICATECHINC₁₅H₁₄O₆290.27 Da
HETEROYOHIMBINES
HIRSUTEINEC₂₂H₂₆N₂O₃366.5 Da
HIRSUTINEC₂₂H₂₈N₂O₃368.5 Da
INDOLEC₈H₇N117.15 Da
ISOMITRAPHYLLINEC₂₁H₂₄N₂O₄368.4 Da
ISOMITRAPHYLLINE-N-OXIDEC₂₁H₂₄N₂O₅384.4 Da
ISOPTEROPODINEC₂₁H₂₄N₂O₄368.4 Da
ISORHYNCHOPHYLLINEC₂₂H₂₈N₂O₄384.5 Da
ISORHYNCHOPHYLLINE-N-OXIDEC₂₂H₂₈N₂O₅400.5 Da
KAEMPFEROLC₁₅H₁₀O₆286.24 Da
MITRAPHYLLINEC₂₁H₂₄N₂O₄368.4 Da
OXINDOLEC₈H₇NO133.15 Da
PROANTHOCYANIDIN-A1C₃₀H₂₄O₁₂576.5 Da
PROANTHOCYANIDIN-B1C₃₀H₂₆O₁₂578.5 Da
PROANTHOCYANIDIN-B2C₃₀H₂₆O₁₂578.5 Da
PROANTHOCYANIDIN-B4C₃₀H₂₆O₁₂578.5 Da
PTEROPODINEC₂₁H₂₄N₂O₄368.4 Da
QUINOVIC ACID-3-BETA-D-[BETA-D-GLUCOSYL-(1-3)-BETA-D-FUCOPYRANOSYL]-(27-1)-BETA-D-GLUCOSYL ESTER
QUINOVIC ACID-3-BETA-O-BETA-D-FUCOPYRANOSYL-(27-1)-BETA-D-GLUCOSIDE
QUINOVIC-ACID-3BETA-O-(BETA-D-GLUCOPYRANOSYL-(1->3)BETA-D-FUCOPYRANOSYL-(27->1)BETA-D-GLUCOPYRANOSYLESTER
QUINOVIC-ACID-3BETA-O-BETA-D-FUCOPYRANOSIDE
QUINOVIC-ACID-3BETA-O-BETA-D-FUCOPYRANOSYL-(27->1)BETA-D-GLUCOPYRANOSYLESTER
QUINOVIC-ACID-3BETA-O-BETA-D-QUINOVOPYRANOSIDE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources