Yellow Vine

Botanical Overview

Yellow Vine (Tripterygium wilfordiim) is a species in the Celastraceae family. The staff-vine family (Celastraceae) includes shrubs, trees, and vines with simple, opposite or alternate leaves and small flowers. The fruits are often brightly colored capsules that split open to reveal seeds with fleshy arils. Many species produce alkaloids and terpenoids with insecticidal and medicinal properties. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 23 compounds in this species, suggesting potential medicinal value.

Family Context

The Celastraceae family is widely distributed. Notable medicinal members include:

Active Compounds

Phytochemical research has identified 23 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Phenolic: antioxidant compounds that neutralize free radicals
  • Terpene: aromatic compounds with anti-inflammatory and antimicrobial properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. The limited documentation available for this species represents an opportunity for ethnobotanical research.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Complete Chemical Inventory

CompoundFormulaMW
(+)-SYRINGARESINOLC₂₂H₂₆O₈418.4 Da
(-)-LIRIORESINOL
CELABENZINEC₂₃H₂₉N₃O₂379.5 Da
CELAFAURINE
CELASTROLC₂₉H₃₈O₄450.6 Da
NEOTRIPTOPHENOLIDEC₂₁H₂₆O₄342.4 Da
TRIPDIOLIDEC₂₀H₂₄O₇376.4 Da
TRIPTERIGINE
TRIPTOLIDEC₂₀H₂₄O₆360.4 Da
TRIPTOLIDENOLC₂₀H₂₄O₇376.4 Da
TRIPTONIDEC₂₀H₂₂O₆358.4 Da
TRIPTONOLIDEC₂₀H₂₂O₄326.4 Da
TRIPTONOTOTERPENE
TRIPTONOTOTERPENE-METHYL-ETHER
TRIPTOPHENOLIDEC₂₀H₂₄O₃312.4 Da
TRIPTOPHENOLIDE-METHYL-ETHERC₂₁H₂₆O₃326.4 Da
WILFODEINE
WILFORDINEC₄₃H₄₉NO₁₉883.8 Da
WILFORGINEC₄₁H₄₇NO₁₉857.8 Da
WILFORINEC₄₃H₄₉NO₁₈867.8 Da
WILFORLIDES
WILFORTRINEC₄₁H₄₇NO₂₀873.8 Da
WILFORZINE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources