Botanical Overview
Puncture-vine (Tribulus terrestris) is a flowering plant in the Zygophyllaceae family. Traditional medicine systems have documented several valuable applications for this species, supported by its observed therapeutic effects. This species belongs to the Zygophyllaceae family, a group of flowering plants.

General Description
It is adapted to thrive in dry climate locations in which few other plants can survive, and is a highly invasive species. Native to warm temperate and tropical regions in southern Eurasia and Africa, it has been unintentionally introduced to North America and Australia. T. terrestris is widely known as a noxious weed because of its small woody fruit – the bur – having long sharp and strong spines which easily penetrate surfaces, such as bare feet or thin shoes of crop workers and other pedestrians, the rubber of bicycle tires, and the mouths and skin of grazing animals.
Family Context
The Zygophyllaceae family is widely distributed. Notable medicinal members include:
- Harmel — 40 documented uses
- Chaparral — 18 documented uses
- Fagonia cretica — 15 documented uses
Geographic Distribution
Puncture-vine has been recorded in 10 countries and territories worldwide, including Australia, China, Spain, France, Greece, and others.
Traditional Uses
Puncture-vine has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.
Digestive health.
- Carminative
- Stomachic
For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.
Respiratory conditions.
- Cough
Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.
Skin and wound care.
- Psoriasis
- Scabies
- Skin
For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.
Active Compounds
Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Flavonoid: antioxidant compounds that protect cells from oxidative damage
- Sterol: cholesterol-like compounds with anti-inflammatory properties
- Alkaloid: nitrogenous compounds with diverse pharmacological activities