Puncture-vine

Botanical Overview

Puncture-vine (Tribulus terrestris) is a flowering plant in the Zygophyllaceae family. Traditional medicine systems have documented several valuable applications for this species, supported by its observed therapeutic effects. This species belongs to the Zygophyllaceae family, a group of flowering plants.

General Description

It is adapted to thrive in dry climate locations in which few other plants can survive, and is a highly invasive species. Native to warm temperate and tropical regions in southern Eurasia and Africa, it has been unintentionally introduced to North America and Australia. T. terrestris is widely known as a noxious weed because of its small woody fruit – the bur – having long sharp and strong spines which easily penetrate surfaces, such as bare feet or thin shoes of crop workers and other pedestrians, the rubber of bicycle tires, and the mouths and skin of grazing animals.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Zygophyllaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Puncture-vine has been recorded in 10 countries and territories worldwide, including Australia, China, Spain, France, Greece, and others.

Traditional Uses

Puncture-vine has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.

Digestive health.

  • Carminative
  • Stomachic

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Cough

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Psoriasis
  • Scabies
  • Skin

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Australia, China, Spain, France, Greece, Italy, Mexico, Pakistan, United States, South Africa.

Complete Use Records

CategoryCultural Context
DiureticChina, Elsewhere, Iraq, Sudan
TonicChina, Elsewhere, Iraq
UrogenitalKurdistan, Spain
CoughChina, Iraq
Ache(Head)China
AlterativeChina
AnemiaChina
AperientElsewhere
AphrodisiacIraq
Bright's DiseaseElsewhere
CancerIndia
CarminativeChina
DysuriaIraq
HepatitisChina
InflammationChina
LactogogueChina
PotherbLesotho
PsoriasisChina
RefrigerantIraq
ScabiesChina
SkinChina
SpermatorrheaChina
StomachicElsewhere
StomatitisChina
VertigoChina
AstringentChina
CongestionChina
GonorrheaIraq
LungChina
RheumatismLesotho

Complete Chemical Inventory

CompoundFormulaMW
25-D-SPIROSTA-3,5-DIENE
ASCORBIC-ACIDC₆H₈O₆176.12 Da
ASH
ASPARTIC-ACIDC₄H₇NO₄133.10 Da
ASTRAGALINC₂₁H₂₀O₁₁448.4 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CALCIUMCa40.08 Da
CAMPESTEROLC₂₈H₄₈O400.7 Da
CARBOHYDRATES
CHLOROGENINC₂₇H₄₄O₄432.6 Da
CRACILLIN
DAUCOSTEROLC₃₅H₆₀O₆576.8 Da
DESOXYDIOSGENIN
DIOSGENINC₂₇H₄₂O₃414.6 Da
DIOSGIN
FATC₁₆H₃₂O₂256.42 Da
FIBER
GITOGENINC₂₇H₄₄O₄432.6 Da
GLUTAMIC-ACIDC₅H₉NO₄147.13 Da
HARMANC₁₂H₁₀N₂182.22 Da
HARMINEC₁₃H₁₂N₂O212.25 Da
HECOGENINC₂₇H₄₂O₄430.6 Da
IRONFe55.84 Da
KAEMPFEROLC₁₅H₁₀O₆286.24 Da
KAEMPFEROL-3-0-GLUCOSIDE
KAEMPFEROL-3-0-RUTINOSIDE
KAEMPFEROL-3-BETA-D-(6'P-COUMAROYL)-GLUCOSIDE
LINOLEIC-ACIDC₁₈H₃₂O₂280.4 Da
NEOGITOGENINC₂₇H₄₄O₄432.6 Da
NEOHECOGENIN-3-O-BETA-D-GLUCOPYRANOSIDE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources