Iboga

Botanical Overview

Iboga (Tabernanthe iboga) belongs to the Apocynaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The dogbane family (Apocynaceae) includes herbs, shrubs, vines, and trees with milky sap containing alkaloids and cardiac glycosides. The flowers are typically five-petaled and often showy with a tubular corolla. Many species in this family are highly toxic but also source of important cardiac medications.

General Description

A member of the Apocynaceae family indigenous to Gabon, the Democratic Republic of Congo, and the Republic of Congo, it is cultivated across Central Africa for use in traditional medicine and rituals.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Apocynaceae family is primarily tropical and subtropical. Notable medicinal members include:

Geographic Distribution

Iboga has been recorded in 10 countries and territories worldwide, including Angola, Congo (DRC), Central African Republic, Congo, Ivory Coast, and others.

Traditional Uses

Iboga has been traditionally used for fever management, reproductive health, and cardiovascular health, among other applications.

Fever management.

  • Fever

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Reproductive health.

  • Aphrodisiac

In traditional contexts, reproductive health applications typically involve internal preparations such as teas or decoctions. The herb may be taken at specific times during the menstrual cycle.

Cardiovascular health.

  • Hypertension

Active Compounds

Phytochemical research has identified 24 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
  • Tannin: astringent compounds that tighten tissues and resist infection
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Angola, Congo (DRC), Central African Republic, Congo, Ivory Coast, Cameroon, Gabon, Equatorial Guinea, United States, Unknown.

Complete Use Records

CategoryCultural Context
AphrodisiacAfrica, English, Gabon, Zaire
FeverAfrica, English
ApertifElsewhere
CNS stimulantGabon
ConvalescenceElsewhere
DebilityAfrica
FatalityGabon
HypertensionElsewhere
NeurastheniaElsewhere
TonicAfrica
FluElsewhere

Complete Chemical Inventory

CompoundFormulaMW
ALKALOIDS
DESMETHOXYIBOLUTEINE
EPIIBOGAMINE
GABONINE
HYDROXYINDOLEINIBOGAINE
HYDROXYINDOLEINIBOGAMINE
IBAGAMINE
IBOCHINE
IBOGAINEC₂₀H₂₆N₂O310.4 Da
IBOGALINEC₂₁H₂₈N₂O₂340.5 Da
IBOGAMINEC₁₉H₂₄N₂280.4 Da
IBOLUTEINEC₂₀H₂₆N₂O₂326.4 Da
IBOPHYLLIDINE
IBOXYGAINEC₂₀H₂₆N₂O₂326.4 Da
IBOXYPHYLLINE
KIMVULINEC₂₀H₂₆N₂O₂326.4 Da
KISANTINE
PANDOLINE
TABERNANTHINEC₂₀H₂₆N₂O310.4 Da
TANNIN
TUBOTAIWINEC₂₀H₂₄N₂O₂324.4 Da
VOACANGINEC₂₂H₂₈N₂O₃368.5 Da
VOACRISTINEC₂₂H₂₈N₂O₄384.5 Da
VOAPHYLLINEC₁₉H₂₄N₂O296.4 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources