Botanical Overview
Kombe Arrow Poison (Strophanthus kombe) belongs to the Apocynaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The dogbane family (Apocynaceae) includes herbs, shrubs, vines, and trees with milky sap containing alkaloids and cardiac glycosides. The flowers are typically five-petaled and often showy with a tubular corolla. Many species in this family are highly toxic but also source of important cardiac medications.

General Description
S. kombe contains a cardiac glycoside which directly affects the heart. Historically, both the seeds and roots of the plant were used in the preparation of poison arrowheads used for hunting. Today, the seeds are used pharmaceutically for patients with certain heart conditions that affect blood circulation. The seeds are traded primarily with Europe, but have also been exported to the United States and Japan.
Family Context
The Apocynaceae family is primarily tropical and subtropical. Notable medicinal members include:
- Alstonia scholaris — 42 documented uses
- Madagascar Periwinkle — 40 documented uses
- Oleander — 30 documented uses
- African Snakeroot — 28 documented uses
Geographic Distribution
Kombe Arrow Poison has been recorded in 10 countries and territories worldwide, including Angola, Congo (DRC), Kenya, Malawi, Mozambique, and others.
Traditional Uses
Kombe Arrow Poison has been traditionally used for urinary tract health and cardiovascular health.
Urinary tract health.
- Diuretic
Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.
Cardiovascular health.
- Heart
Active Compounds
Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Flavonoid: antioxidant compounds that protect cells from oxidative damage
- Alkaloid: nitrogenous compounds with diverse pharmacological activities