Ouabain

Botanical Overview

Ouabain (Strophanthus gratus) belongs to the Apocynaceae family. Limited but reliable traditional records indicate this plant has recognized medicinal applications in one or more healing traditions. The dogbane family (Apocynaceae) includes herbs, shrubs, vines, and trees with milky sap containing alkaloids and cardiac glycosides. The flowers are typically five-petaled and often showy with a tubular corolla. Many species in this family are highly toxic but also source of important cardiac medications.

General Description

Strophanthus gratus is a plant in the dogbane family Apocynaceae.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Apocynaceae family is primarily tropical and subtropical. Notable medicinal members include:

Active Compounds

Phytochemical research has identified 15 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Complete Use Records

CategoryCultural Context
Poison(Arrow)Africa

Complete Chemical Inventory

CompoundFormulaMW
ACOLONGIFLOROSIDE-KC₂₉H₄₄O₁₂584.7 Da
BIPINDOSIDEC₂₉H₄₄O₁₀552.7 Da
CHOLINEC₅H₁₄NO+104.17 Da
GLYCOSIDESC₂₉H₄₄O₁₂584.7 Da
LINOLEIC-ACIDC₁₈H₃₂O₂280.4 Da
OLEIC-ACIDC₁₈H₃₄O₂282.5 Da
OUABAINC₂₉H₄₄O₁₂584.7 Da
SARHAMNOLOSIDE
SARMENTOLOSIDEC₂₉H₄₄O₁₁568.7 Da
SARMENTOSIDE-EC₂₉H₄₀O₁₁564.6 Da
SARNOVIDEC₃₀H₄₆O₉550.7 Da
STROGOSIDEC₂₉H₄₀O₁₂580.6 Da
STROPHANTHINIC-ACID
THOLLOSIDEC₂₉H₄₂O₁₁566.6 Da
TRIGONELLINEC₇H₇NO₂137.14 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources