Stephania

Botanical Overview

Stephania (Stephania tetrandra) belongs to the Menispermaceae family. Limited but reliable traditional records indicate this plant has recognized medicinal applications in one or more healing traditions. This species belongs to the Menispermaceae family, a group of flowering plants.

General Description

It includes a single species, Botryodiscia tetrandra, is a herbaceous perennial vine or scrambling subshrub native native to southern China, Hainan, Taiwan, and Vietnam. It grows from a short, woody caudex, climbing to a height of around three meters. The leaves are arranged spirally on the stem, and are peltate, i. e. with the leaf petiole attached near the centre of the leaf. Its root is used in traditional Chinese medicine (TCM).

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Menispermaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Stephania has been recorded in 6 countries and territories worldwide, including China, Hong Kong, Japan, Taiwan, United States, and others.

Traditional Uses

Stephania has been traditionally used for urinary tract health and cardiovascular health.

Urinary tract health.

  • Edema

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Cardiovascular health.

  • Hypertension

Active Compounds

Phytochemical research has identified 9 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: China, Hong Kong, Japan, Taiwan, United States, Vietnam.

Complete Use Records

CategoryCultural Context
EdemaChina
HypertensionChina
AcheChina
Beri-BeriChina
ArthrodyniaChina
NumbnessChina

Complete Chemical Inventory

CompoundFormulaMW
CYCLANOLINEC₂₀H₂₄NO₄+342.4 Da
DIMETHYLTETRANDRINE
FANGCHINOLINEC₃₇H₄₀N₂O₆608.7 Da
HANDFANGCHINS
ISOTETRANDRINEC₃₈H₄₂N₂O₆622.7 Da
MENISIDINEC₃₇H₄₀N₂O₆608.7 Da
MENISINE
STEARIC-ACID-GLYCERIDES
TETRANDRINEC₃₈H₄₂N₂O₆622.7 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources