Japanese Tape-Vine

Botanical Overview

Japanese Tape-Vine (Stephania japonica) belongs to the Menispermaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. This species belongs to the Menispermaceae family, a group of flowering plants.

General Description

Stephania japonica, known as snake vine, is a vine often seen in sheltered areas near the sea.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Menispermaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Japanese Tape-Vine has been recorded in 10 countries and territories worldwide, including Australia, China, Indonesia, India, Japan, and others.

Traditional Uses

Japanese Tape-Vine has been traditionally used for skin and wound care, fever management, and immune system support.

Skin and wound care.

  • Itch

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Fever management.

  • Fever

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Immune system support.

  • Cancer
  • Tumor

Immune support involves taking the herb as a decoction or tincture over extended periods. The active compounds stimulate immune cell activity and provide antimicrobial protection.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Australia, China, Indonesia, India, Japan, South Korea, French Polynesia, Papua New Guinea, Thailand, Taiwan.

Complete Use Records

CategoryCultural Context
AstringentElsewhere
CancerJapan
FeverElsewhere
ItchPhilippines
TumorElsewhere
UrogenitalElsewhere

Complete Chemical Inventory

CompoundFormulaMW
16-OXOHASUBONINE
16-OXOPROTOMETAPHANINE
AKNADICINEC₁₉H₂₃NO₅345.4 Da
AKNADINE
AKNADININEC₂₀H₂₅NO₅359.4 Da
ALKALOIDS
CYCLANOLINEC₂₀H₂₄NO₄+342.4 Da
CYCLEANINEC₃₈H₄₂N₂O₆622.7 Da
D-FANGCHINOLINE
D-TETRANDRINEC₃₈H₄₂N₂O₆622.7 Da
DEHYDROEPISTEPHANINE
EPISTEPHAMIERSINEC₂₁H₂₇NO₆389.4 Da
EPISTEPHANINEC₃₇H₃₈N₂O₆606.7 Da
HASUBANONINEC₂₁H₂₇NO₅373.4 Da
HERNANDOLINEC₂₀H₂₅NO₅359.4 Da
HOMOEPISTEPHANINE
HOMOSTEPHANOLINEC₂₀H₂₅NO₅359.4 Da
HYPOEPISTEPHANINEC₃₆H₃₆N₂O₆592.7 Da
INSULARINEC₃₈H₄₀N₂O₆620.7 Da
ISOCHONDRODENDRINEC₃₆H₃₈N₂O₆594.7 Da
ISOTRILOBINEC₃₆H₃₆N₂O₅576.7 Da
L-QUERCITOL
METAPHANINEC₁₉H₂₃NO₅345.4 Da
N-NOR-1,2-DEHYDROEPISTEPHANINE
OBAMEGINEC₃₆H₃₈N₂O₆594.7 Da
OXOSTEPHAMIERSINEC₂₁H₂₅NO₇403.4 Da
OXOSTEPHANINEC₁₈H₁₁NO₄305.3 Da
PLASTOQUINONEC₅₃H₈₀O₂749.2 Da
PROMETAPHANINEC₂₀H₂₅NO₅359.4 Da
PROTOSTEPHANABERRINE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources