Bitter Nightshade

Also known as: Bittersweet

Botanical Overview

Bitter Nightshade (Solanum dulcamara) is a flowering plant in the Solanaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The nightshade family (Solanaceae) includes herbs, shrubs, and small trees with alternate leaves and star-shaped or trumpet-shaped flowers. The fruits are typically berries or capsules. Many species produce potent alkaloids including tropanes, solanines, and nicotine, making this family both medicinally valuable and potentially toxic.

General Description

Common names include bittersweet, bittersweet nightshade, bitter nightshade, blue bindweed, Amara Dulcis, climbing nightshade, felonwort, fellenwort, felonwood, poisonberry, poisonflower, scarlet berry, snakeberry, trailing bittersweet, trailing nightshade, violet bloom, and woody nightshade. It is native to Europe and Asia, and widely naturalised elsewhere, including North America.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Solanaceae family is widely distributed worldwide. Notable medicinal members include:

Geographic Distribution

Bitter Nightshade has been recorded in 10 countries and territories worldwide, including Belgium, Canada, Germany, Denmark, France, and others.

Traditional Uses

Bitter Nightshade has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.

Digestive health.

  • Laxative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Bronchitis

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Skin
  • Sore

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Narcotic, Poison, Emetic. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Belgium, Canada, Germany, Denmark, France, United Kingdom, Netherlands, Russia, Sweden, United States.

Complete Use Records

CategoryCultural Context
DiureticEurasia, Turkey
NarcoticSpain, Turkey
PoisonElsewhere, Turkey
RheumatismElsewhere, Iraq
SedativeElsewhere, Eurasia
SkinElsewhere, Iraq
TumorElsewhere, Europe
WartDenmark, Elsewhere
AnalgesicElsewhere
AnaphrodisiacIraq
BronchitisIraq
CancerChina
DepurativeTurkey
DiaphoreticEurasia
EmeticIraq
ExcrescenceIceland
EyeChina
FeverChina
HypnoticEurasia
LaxativeTurkey
MalariaChina
ResolventTurkey
SoreChina
StimulantTurkey
SwellingChina
Tumor(Breast)Chile
AntidoteChina
RefrigerantChina
SudorificTurkey
AlterativeTurkey

Complete Chemical Inventory

CompoundFormulaMW
15ALPHA-HYDROXYSOLADULCIDINE
15ALPHA-HYDROXYSOLASODINE
15ALPHA-HYDROXYTOMATADENOL
15ALPHA-HYDROXYTOMATADIDINE
2,4-METHYLENE-CHOLESTEROLC₂₈H₄₆O398.7 Da
24-METHYLENE-CYCLOARTENOL
3,5-TOMATIDIENE
31-NOR-LANOSTEROLC₂₉H₄₈O412.7 Da
3BETA-5-TOMATIDEN-OL
ALPHA-SOLADULCINE
ALPHA-SOLAMARINEC₄₅H₇₃NO₁₆884.1 Da
ATROPINEC₁₇H₂₃NO₃289.4 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
BETA-SOLADULCINE
BETA-SOLAMARINEC₄₅H₇₃NO₁₅868.1 Da
BRASSICASTEROLC₂₈H₄₆O398.7 Da
CAMPESTEROLC₂₈H₄₈O400.7 Da
CHOLESTEROLC₂₇H₄₆O386.7 Da
CITROSTADIENOLC₃₀H₅₀O426.7 Da
CYCLOARTENOLC₃₀H₅₀O426.7 Da
CYCLOARTENOL-24-DIHYDROLANOSTEROL
D-GALACTOSEC₆H₁₂O₆180.16 Da
D-GLUCOSEC₆H₁₂O₆180.16 Da
D-XYLOSEC₅H₁₀O₅150.13 Da
DIOSGENINC₂₇H₄₂O₃414.6 Da
GAMMA-SOLADULCINE
GAMMA-SOLAMARINEC₃₉H₆₃NO₁₁721.9 Da
GRAMISTEROLC₂₉H₄₈O412.7 Da
ISOFUCOSTEROLC₂₉H₄₈O412.7 Da
L-RHAMNOSEC₆H₁₂O₅164.16 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources