Botanical Overview
Sarsaparilla (Smilax regelii) belongs to the Smilacaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. This species belongs to the Smilacaceae family, a group of flowering plants.

General Description
Common names include sarsaparilla, Honduran sarsaparilla, and Jamaican sarsaparilla.
Family Context
The Smilacaceae family is widely distributed. Notable medicinal members include:
- China Root — 37 documented uses
- Sarsaparilla — 1 documented uses
Geographic Distribution
Sarsaparilla has been recorded in 9 countries and territories worldwide, including Belize, Costa Rica, Guatemala, Honduras, Jamaica, and others.
Traditional Uses
Sarsaparilla has been traditionally used for skin and wound care, pain and inflammation, and reproductive health, among other applications.
Skin and wound care.
- Skin
For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.
Pain and inflammation.
- Rheumatism
For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.
Reproductive health.
- Venereal
In traditional contexts, reproductive health applications typically involve internal preparations such as teas or decoctions. The herb may be taken at specific times during the menstrual cycle.
Active Compounds
Phytochemical research has identified 2 compounds in this species: beta-sitosterol, stigmasterol.
The identified compounds include the following categories:
- Sterol: cholesterol-like compounds with anti-inflammatory properties