Botanical Overview
Sarsaparilla (Smilax officinalis) belongs to the Smilacaceae family. Limited but reliable traditional records indicate this plant has recognized medicinal applications in one or more healing traditions. This species belongs to the Smilacaceae family, a group of flowering plants.

General Description
A vine reaching 50 m (160 ft) as it climbs trees into the canopy, its roots are collected and used to make traditional medicines and, like other Smilax species, the soft drink sarsaparilla.
Family Context
The Smilacaceae family is widely distributed. Notable medicinal members include:
- China Root — 37 documented uses
- Sarsaparilla — 9 documented uses
Geographic Distribution
Sarsaparilla has been recorded in 10 countries and territories worldwide, including Brazil, Colombia, Costa Rica, Ecuador, Guatemala, and others.
Traditional Uses
Sarsaparilla has been traditionally used for immune system support.
Immune system support.
- Tumor
Immune support involves taking the herb as a decoction or tincture over extended periods. The active compounds stimulate immune cell activity and provide antimicrobial protection.
Active Compounds
Phytochemical research has identified 27 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Flavonoid: antioxidant compounds that protect cells from oxidative damage
- Alkaloid: nitrogenous compounds with diverse pharmacological activities