Simaruba Bark

Botanical Overview

Simaruba Bark (Simarouba glauca) is a flowering plant in the Simaroubaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The quassia family (Simaroubaceae) includes trees and shrubs with bitter bark, compound leaves, and small, unisexual flowers. The fruits are typically drupes or samaras. Many species contain quassinoids, intensely bitter compounds with antimalarial and anticancer activity.

General Description

Common names include paradise-tree, dysentery-bark, and bitterwood. The tree is well suited for warm, humid, tropical regions. Its cultivation depends on rainfall distribution, water holding capacity of the soil, and sub-soil moisture. It is suited for temperature range of 10 to 40 °C (50 to 104 °F), and can grow at elevations from sea level to 1,000 m (3,300 ft). It grows 40 to 50 ft (12 to 15 m) tall and has a span of 25 to 30 ft (7. 6 to 9. 1 m). It bears yellow flowers and purple elongated oval fleshy fruits.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Simaroubaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Simaruba Bark has been recorded in 10 countries and territories worldwide, including Belize, Costa Rica, Cuba, Dominican Republic, Guatemala, and others.

Traditional Uses

Simaruba Bark has been traditionally used for digestive health, pain and inflammation, and fever management, among other applications.

Digestive health.

  • Dyspepsia
  • Colic
  • Diarrhea
  • Dysentery
  • Stomachic
  • Purgative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Pain and inflammation.

  • Anodyne
  • Rheumatism

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Fever management.

  • Malaria
  • Fever

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Active Compounds

Phytochemical research has identified 15 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Emetic, Purgative. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Belize, Costa Rica, Cuba, Dominican Republic, Guatemala, Honduras, Jamaica, Mexico, El Salvador, United States.

Complete Use Records

CategoryCultural Context
MalariaCostarica, Dominican Republic, Elsewhere, Mexico
AmebiasisCosta Rica, Mexico
DyspepsiaHaiti, Mexico
FeverHaiti, Mexico
Ache(Body)Haiti
AnemiaHaiti
AnodyneHaiti
ColicDominican Republic
DiarrheaDominican Republic
DysenteryHaiti
EmeticHaiti
EmmenagogueHaiti
RheumatismHaiti
SoapElsewhere
StomachicSalvador
SudorificHaiti
PurgativeHaiti
IntoxicantSalvador
GonorrheaDominican Republic

Complete Chemical Inventory

CompoundFormulaMW
15-HYDROXYAILANTHONE
15-O-BETA-D-GLUCOPYRANOSYLGLAUCARUBOL
15-O-BETA-D-GLUCOPYRANOSYLGLAUCARUBOLONE
ARACHIDIC-ACIDC₂₀H₄₀O₂312.5 Da
DELTA-13(18)-GLAUCARUBIN
FATC₁₆H₃₂O₂256.42 Da
GLAUCARUBINC₂₅H₃₆O₁₀496.5 Da
GLAUCARUBINONEC₂₅H₃₄O₁₀494.5 Da
GLAUCARUBOLONEC₂₀H₂₆O₈394.4 Da
LINOLEIC-ACIDC₁₈H₃₂O₂280.4 Da
LINOLENIC-ACIDC₁₈H₃₀O₂278.4 Da
OLEIC-ACIDC₁₈H₃₄O₂282.5 Da
PALMITIC-ACIDC₁₆H₃₂O₂256.42 Da
PALMITOLEIC-ACIDC₁₆H₃₀O₂254.41 Da
STEARIC-ACIDC₁₈H₃₆O₂284.5 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources