Coffee Senna

Botanical Overview

Coffee Senna (Senna occidentalis) is a species in the Fabaceae family. The legume family (Fabaceae) includes trees, shrubs, and herbs that produce pods (legumes) and form nitrogen-fixing root nodules through symbiosis with bacteria. The flowers are typically pea-shaped with five petals. This large family provides food staples, timber, and numerous medicinal species. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 30 compounds in this species, suggesting potential medicinal value.

General Description

It is a shrub with pinnate leaves, with three to seven pairs of broadly elliptic to egg-shaped leaflets, and yellow flowers arranged in groups of two to four, with six fertile stamens in each flower. It is an aggressive, pantropical weed.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Fabaceae family is large and globally distributed. Notable medicinal members include:

Geographic Distribution

Coffee Senna has been recorded in 10 countries and territories worldwide, including Australia, Benin, Brazil, China, India, and others.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Australia, Benin, Brazil, China, India, Mexico, Nepal, Saudi Arabia, Tanzania, United States.

Complete Chemical Inventory

CompoundFormulaMW
1,7-DIHYDROXY-5-METHOXYCARBONYL-3-METHYLXANTHONEC₁₆H₁₂O₆300.26 Da
4,4',5,5'-TETRAHYDROXY-2,2'-DIMETHYL-1,1'-BIANTHRAQUINONE
4-O-BETA-D-MANNOPYRANOSYL-D-MANNOPYRANOSEC₁₂H₂₂O₁₁342.30 Da
6-O-ALPHA-D-GALACTOPYRANOSYL-D-MANNOPYRANOSEC₁₂H₂₂O₁₁342.30 Da
ACHROSINE
ALOE-EMODINC₁₅H₁₀O₅270.24 Da
ALPHA-3-SITOSTEROL
ANTHRAQUINONESC₁₄H₈O₂208.21 Da
ANTHRONES
APIGENIN-C-GLYCOSIDE
BETA-SITOSTEROL-ALPHA-GLUCOSIDE
BIANTHRAQUINONEC₂₈H₁₄O₄414.4 Da
CALCIUMCa40.08 Da
CAMPESTEROLC₂₈H₄₈O400.7 Da
CASSIOLLINC₁₆H₁₂O₆300.26 Da
CHRYSAROBINC₁₅H₁₂O₃240.25 Da
CHRYSOPHANOLC₁₅H₁₀O₄254.24 Da
COPPERCu63.55 Da
EMODINC₁₅H₁₀O₅270.24 Da
FATC₁₆H₃₂O₂256.42 Da
FUNICULOSIN
GAMMA-SITOSTEROLC₂₉H₅₀O414.7 Da
GLUCOSEC₆H₁₂O₆180.16 Da
GUM
HELMINTHOSPORINC₁₅H₁₀O₅270.24 Da
IRONFe55.84 Da
ISLANDICINC₁₅H₁₀O₅270.24 Da
JACEIDIN-7-RHAMNOSIDEC₂₄H₂₆O₁₂506.5 Da
LINOLEIC-ACIDC₁₈H₃₂O₂280.4 Da
LINOLENIC-ACIDC₁₈H₃₀O₂278.4 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources