Hsuan-Shen

Also known as: Yuan-Shen

Botanical Overview

Hsuan-Shen (Scrophularia buergeriana) belongs to the Scrophulariaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The figwort family (Scrophulariaceae) includes herbs and shrubs with alternate or opposite leaves and two-lipped, often showy flowers. The fruits are typically capsules with many small seeds. Many species contain iridoid glycosides and cardiac glycosides with medicinal properties.

Family Context

The Scrophulariaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Hsuan-Shen has been recorded in 8 countries and territories worldwide, including China, Spain, Hong Kong, Japan, South Korea, and others.

Traditional Uses

Hsuan-Shen has been traditionally used for fever management.

Fever management.

  • Febrifuge

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Active Compounds

Phytochemical research has identified 17 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: China, Spain, Hong Kong, Japan, South Korea, Russia, Singapore, Taiwan.

Complete Use Records

CategoryCultural Context
FebrifugeElsewhere
AntiphlogisticElsewhere

Complete Chemical Inventory

CompoundFormulaMW
8-(O-METHYL-P-COUMAROYL)-HARPAGIDE
ARSENICAs74.92159 Da
CALCIUMCa40.08 Da
COPPERCu63.55 Da
FRUCTOSEC₆H₁₂O₆180.16 Da
GLUCOSEC₆H₁₂O₆180.16 Da
HARPAGIDEC₁₅H₂₄O₁₀364.34 Da
HARPAGOSIDEC₂₄H₃₀O₁₁494.5 Da
IRONFe55.84 Da
MAGNESIUMMg24.305 Da
MANGANESEMn54.93804 Da
OLIGOSACCHARIDE
P-METHOXY-CINNAMIC-ACID
POTASSIUMK39.0983 Da
SODIUMNa22.9897693 Da
STACHYOSEC₂₄H₄₂O₂₁666.6 Da
ZINCZn65.4 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources