Clary Sage

Botanical Overview

Clary Sage (Salvia sclarea) belongs to the Lamiaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The mint family (Lamiaceae) includes aromatic herbs and shrubs with square stems, opposite leaves, and two-lipped flowers. Many species produce essential oils in glandular trichomes on their leaves and stems. This family is one of the most important sources of culinary and medicinal herbs worldwide.

General Description

It is native to the northern Mediterranean Basin and to some areas in north Africa and Central Asia. The plant has long been cultivated as an herb and is currently grown for its essential oil.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Lamiaceae family is large and widely distributed. Notable medicinal members include:

  • Basil — 86 documented uses
  • Rosemary — 60 documented uses
  • Agbo — 54 documented uses
  • Sage — 49 documented uses

Geographic Distribution

Clary Sage has been recorded in 10 countries and territories worldwide, including Switzerland, Germany, Spain, France, Greece, and others.

Traditional Uses

Clary Sage has been traditionally used for digestive health, respiratory conditions, and nervous system disorders, among other applications.

Digestive health.

  • Stomachic

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Catarrh

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Nervous system disorders.

  • Spasm

Nervous system support involves taking the herb as a warm tea, often in the evening or before bed. The calming compounds interact with neurotransmitter systems to promote relaxation and restful sleep.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Switzerland, Germany, Spain, France, Greece, Israel, Italy, Turkey, Ukraine, United States.

Complete Use Records

CategoryCultural Context
AstringentTurkey
CosmeticEurope
DebilitySpain
EmmenagogueTurkey
SoapEurope
SpasmTurkey
StimulantTurkey
StomachicTurkey
AntisepticTurkey
PerspirationTurkey
CancerUk(Wales)
CatarrhTurkey

Complete Chemical Inventory

CompoundFormulaMW
(1R,5R)-EPOXYSALVIAL-4(14)-EN-1-ONE
(2R,5E)-EPOXYCARYOPHYLL-5-EN-12-AL
(2R,5E)-EPOXYCARYOPHYLL-5-ENE
(2S,5E)-EPOXYCARYOPHYLL-5-EN-12-AL
1,8-CINEOLEC₁₀H₁₈O154.25 Da
3-OCTANOLC₈H₁₈O130.23 Da
ACETIC-ACID-ESTER
ALPHA-BISABOLOLC₁₅H₂₆O222.37 Da
ALPHA-PINENEC₁₀H₁₆136.23 Da
ALPHA-TERPINEOLC₁₀H₁₈O154.25 Da
ALPHA-TERPINYL-ACETATEC₁₂H₂₀O₂196.29 Da
ARACHIDIC-ACIDC₂₀H₄₀O₂312.5 Da
BEHENIC-ACIDC₂₂H₄₄O₂340.6 Da
BENZALDEHYDEC₇H₆O106.12 Da
BETA-CARYOPHYLLENEC₁₅H₂₄204.35 Da
BETA-GURJUENE
BETA-MYRCENEC₁₀H₁₆136.23 Da
BETA-PINENEC₁₀H₁₆136.23 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
BUTYRIC-ACIDC₄H₈O₂88.11 Da
CADINENEC₁₅H₂₆206.37 Da
CAMPHENEC₁₀H₁₆136.23 Da
CAMPHORC₁₀H₁₆O152.23 Da
CAPRYLIC-ACIDC₈H₁₆O₂144.21 Da
CARYOPHYLLENE-OXIDEC₁₅H₂₄O220.35 Da
CEROTINIC-ACIDC₂₆H₅₂O₂396.7 Da
CIS-3-HEXEN-1-OLC₆H₁₂O100.16 Da
CIS-ALLO-OCIMENE
CIS-BETA-OCIMENEC₁₀H₁₆136.23 Da
CIS-LINALOL-OXIDE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources