Sage

Botanical Overview

Sage (Salvia officinalis) is a flowering plant in the Lamiaceae family. This plant has earned a place in traditional medicine through its consistent therapeutic benefits, recorded across multiple cultures. The mint family (Lamiaceae) includes aromatic herbs and shrubs with square stems, opposite leaves, and two-lipped flowers. Many species produce essential oils in glandular trichomes on their leaves and stems. This family is one of the most important sources of culinary and medicinal herbs worldwide.

General Description

It is a member of the mint family (Lamiaceae) and native to the Mediterranean region, though it has been naturalized in many places throughout the world. It has a long history of culinary use, and in modern times it has been used as an ornamental garden plant. The common name “sage” is also used for closely related species and cultivars.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Lamiaceae family is large and widely distributed. Notable medicinal members include:

Geographic Distribution

Sage has been recorded in 10 countries and territories worldwide, including Austria, Switzerland, Czech Republic, Germany, Spain, and others.

Traditional Uses

Sage has been traditionally used for digestive health, respiratory conditions, and fever management, among other applications.

Digestive health.

  • Carminative
  • Stomachic
  • Vermifuge

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Cold

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Fever management.

  • Fever

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Austria, Switzerland, Czech Republic, Germany, Spain, France, Croatia, Italy, Slovakia, United States.

Complete Use Records

CategoryCultural Context
TonicElsewhere, Turkey, US
AntisepticTurkey, US
AstringentElsewhere, Turkey
CarminativeEurope, Turkey
Sore(Throat)Elsewhere, US
StimulantEurope, Turkey
AntioxidantElsewhere
AnydroticTurkey
BaldnessElsewhere
ColdUS
CordialTurkey
DandruffElsewhere
DiaphoreticElsewhere
FeverTurkey
FumitoryElsewhere
GingivitisElsewhere
Hair-OilElsewhere
HemostatTurkey
InsecticideElsewhere
MedicineUS(Appalachia)
NauseaTurkey
Night-SweatUS
PerspirationTurkey
ResolventTurkey
StomachicTurkey
ThrushElsewhere
VermifugeUS
VulneraryTurkey
WeaningElsewhere
WenUK

Complete Chemical Inventory

CompoundFormulaMW
(-)-THUJONEC₁₀H₁₆O152.23 Da
1,8-CINEOLC₁₀H₁₈O154.25 Da
1,8-CINEOLEC₁₀H₁₈O154.25 Da
1,8-CINEOLE-SYNTHETASE
1-OCTEN-3-OLC₈H₁₆O128.21 Da
2-ALPHA,3-ALPHA-DIHYDROXY-OLEAN-12-EN-28-OIC-ACID
2-ALPHA-HYDROXY-3-OXO-OLEAN-12-EN-28-OIC-ACID
2-AMINO-ADIPIC-ACID
2-METHYL-3-METHYLENE-5-HEPTANE
2-METHYL-3-METHYLENE-HEPT-CIS-5-ENE
2-METHYL-3-METHYLENE-HEPT-TRANS-5-ENE
3-CARENEC₁₀H₁₆136.23 Da
3-EPIOLEANOLIC-ACIDC₃₀H₄₈O₃456.7 Da
3-ISOTHUJONEC₁₀H₁₆O152.23 Da
5-METHOXYSALVIGENINC₁₉H₁₈O₆342.3 Da
6,7-DIMETHOXY-ROSMANOL
6-METHOXY-GENKWANIN
6-METHOXYGENKWANIN-7-METHYL-ETHER
6-METHOXYLUTEOLINC₁₆H₁₂O₇316.26 Da
6-METHOXYLUTEOLIN-7-METHYL-ETHER
7-METHOXY-ROSMANOL
7-O-ACETYL-HORMINONE
ACETO-HYDROXY-ROYLEANONE
ALANINEC₃H₇NO₂89.09 Da
ALLO-AROMADENDRENEC₁₅H₂₄204.35 Da
ALPHA-AMYRINC₃₀H₅₀O426.7 Da
ALPHA-BETA-THUJONE
ALPHA-CADINOLC₁₅H₂₆O222.37 Da
ALPHA-CEDRENEC₁₅H₂₄204.35 Da
ALPHA-COPAENEC₁₅H₂₄204.35 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources