Bitterwood

Also known as: Quassia

Botanical Overview

Bitterwood (Quassia amara) is a flowering plant in the Simaroubaceae family. Traditional medicine systems have documented several valuable applications for this species, supported by its observed therapeutic effects. The quassia family (Simaroubaceae) includes trees and shrubs with bitter bark, compound leaves, and small, unisexual flowers. The fruits are typically drupes or samaras. Many species contain quassinoids, intensely bitter compounds with antimalarial and anticancer activity.

General Description

The genus was named by Carl Linnaeus who named it after the first botanist to describe it: the Surinamese freedman Graman Quassi. Q. amara is used as insecticide, in traditional medicine and as additive in the food industry.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Simaroubaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Bitterwood has been recorded in 10 countries and territories worldwide, including Brazil, Colombia, Costa Rica, French Guiana, Guyana, and others.

Traditional Uses

Bitterwood has been traditionally used for digestive health, urinary tract health, and fever management, among other applications.

Digestive health.

  • Stomachic
  • Dysentery
  • Dyspepsia
  • Laxative
  • Vermifuge
  • Diarrhea

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Urinary tract health.

  • Diuretic

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Fever management.

  • Fever
  • Malaria

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Active Compounds

Phytochemical research has identified 13 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Sterol: cholesterol-like compounds with anti-inflammatory properties
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Brazil, Colombia, Costa Rica, French Guiana, Guyana, Mexico, Nicaragua, Panama, Suriname, Unknown.

Complete Use Records

CategoryCultural Context
TonicDominican Republic, Elsewhere, Latin America, Mexico, Turkey, Venezuela
FeverDominican Republic, Elsewhere, Panama, Turkey, Venezuela
InsecticideElsewhere, Haiti, Latin America, US
StomachicElsewhere, Latin America, Mexico
Bite(Snake)Elsewhere, Panama
DiureticTurkey, Venezuela
DysenteryTurkey, Venezuela
LiverElsewhere, Panama
MalariaPanama(Choco), Turkey
CarcinomaNc
DigestiveTurkey
DyspepsiaMexico
HyperglycemiaPanama
LaxativeVenezuela
StimulantLatin America
VermifugePanama
VermicideMexico
AstringentTurkey
CancerNc
DiarrheaTurkey
MedicinePanama(Choco)

Complete Chemical Inventory

CompoundFormulaMW
18-HYDROXYQUASSIN
ALKALOIDS
BETA-SITOSTENONEC₂₉H₄₈O412.7 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CALCIUM-TARTRATEC₄H₄CaO₆188.15 Da
GALLIC-ACIDC₇H₆O₅170.12 Da
ISOQUASSINC₂₂H₂₈O₆388.5 Da
MALIC-ACIDC₄H₆O₅134.09 Da
NEOQUASSINC₂₂H₃₀O₆390.5 Da
POTASSIUM-ACETATEC₂H₃KO₂98.14 Da
QUASSINC₂₂H₂₈O₆388.5 Da
QUASSINOLC₂₀H₂₄O₆360.4 Da
QUASSOL

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources