Botanical Overview
Bitterwood (Quassia amara) is a flowering plant in the Simaroubaceae family. Traditional medicine systems have documented several valuable applications for this species, supported by its observed therapeutic effects. The quassia family (Simaroubaceae) includes trees and shrubs with bitter bark, compound leaves, and small, unisexual flowers. The fruits are typically drupes or samaras. Many species contain quassinoids, intensely bitter compounds with antimalarial and anticancer activity.

General Description
The genus was named by Carl Linnaeus who named it after the first botanist to describe it: the Surinamese freedman Graman Quassi. Q. amara is used as insecticide, in traditional medicine and as additive in the food industry.
Family Context
The Simaroubaceae family is widely distributed. Notable medicinal members include:
- Stinktree — 36 documented uses
- Simaruba Bark — 19 documented uses
- Cedron — 10 documented uses
- Bitterwood — 9 documented uses
Geographic Distribution
Bitterwood has been recorded in 10 countries and territories worldwide, including Brazil, Colombia, Costa Rica, French Guiana, Guyana, and others.
Traditional Uses
Bitterwood has been traditionally used for digestive health, urinary tract health, and fever management, among other applications.
Digestive health.
- Stomachic
- Dysentery
- Dyspepsia
- Laxative
- Vermifuge
- Diarrhea
For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.
Urinary tract health.
- Diuretic
Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.
Fever management.
- Fever
- Malaria
Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.
Active Compounds
Phytochemical research has identified 13 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Sterol: cholesterol-like compounds with anti-inflammatory properties