Chinese Mayapple

Botanical Overview

Chinese Mayapple (Podophyllum pleianthum) is a species in the Berberidaceae family. The barberry family (Berberidaceae) includes shrubs and herbs with alternate or basal leaves and yellow wood or roots due to alkaloid content. The flowers have six sepals and six petals arranged in whorls, and the fruits are berries or capsules. Many species produce isoquinoline alkaloids like berberine with antimicrobial activity. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 13 compounds in this species, suggesting potential medicinal value.

General Description

Dysosma pleiantha), the many-flowered Chinese mayapple, is a species of flowering plant in the genus Podophyllum, native to south-central and southeast China, including Taiwan. Shade tolerant, and deer resistant due to its toxicity, it has gained the Royal Horticultural Society’s Award of Garden Merit.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Berberidaceae family is widely distributed in temperate regions. Notable medicinal members include:

Geographic Distribution

Chinese Mayapple has been recorded in China, Hong Kong, Norway, Taiwan, and United States.

Active Compounds

Phytochemical research has identified 13 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: China, Hong Kong, Norway, Taiwan, United States.

Complete Chemical Inventory

CompoundFormulaMW
ASTRAGALINC₂₁H₂₀O₁₁448.4 Da
DESOXYPODOPHYLLOTOXINC₂₂H₂₂O₇398.4 Da
DESOXYPODOPHYLLOTOXIN-4'-METHYL-ESTER
HYPERINC₂₁H₂₀O₁₂464.4 Da
HYPEROSIDEC₂₁H₂₀O₁₂464.4 Da
ISOPICROPODOPHYLLONEC₂₂H₂₀O₈412.4 Da
ISOPICROPODOPHYLLONE-4'-METHYL-ESTER
KAEMPFEROLC₁₅H₁₀O₆286.24 Da
PODOPHYLLOTOXINC₂₂H₂₂O₈414.4 Da
PODOPHYLLOTOXIN-4'-METHYL-ESTER
PODOPHYLLOTOXONEC₂₂H₂₀O₈412.4 Da
PODOPHYLLOTOXONE-4'-METHYL-ESTER
QUERCETINC₁₅H₁₀O₇302.23 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources