Forskohl's Coleus

Also known as: Indian Coleus, False Boldo

Botanical Overview

Forskohl’s Coleus (Plectranthus barbatus) is a species in the Lamiaceae family. The mint family (Lamiaceae) includes aromatic herbs and shrubs with square stems, opposite leaves, and two-lipped flowers. Many species produce essential oils in glandular trichomes on their leaves and stems. This family is one of the most important sources of culinary and medicinal herbs worldwide. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 30 compounds in this species, suggesting potential medicinal value.

General Description

It is known by the common name woolly plectranthus. It produces forskolin, an extract useful for pharmaceutical preparations and research in cell biology.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Lamiaceae family is large and widely distributed. Notable medicinal members include:

  • Basil — 86 documented uses
  • Rosemary — 60 documented uses
  • Agbo — 54 documented uses
  • Sage — 49 documented uses

Geographic Distribution

Forskohl’s Coleus has been recorded in 10 countries and territories worldwide, including Brazil, Eritrea, Ethiopia, India, Kenya, and others.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Further ethnobotanical and pharmacological research may reveal additional therapeutic applications for this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Brazil, Eritrea, Ethiopia, India, Kenya, Sri Lanka, Saudi Arabia, Tanzania, Uganda, South Africa.

Complete Chemical Inventory

CompoundFormulaMW
(+)-FERRUGINOLC₂₀H₃₀O286.5 Da
1,9-DIDEOXY-7-DEACETYL-FORSKOHLIN
1,9-DIDEOXYFORSKOHLIN
20-DEOXOCARNOSOLC₂₀H₂₈O₃316.4 Da
3BETA-HYDROXY-3-DEOXYBARBATUSIN
6BETA,7BETA,9ALPHA-TRIHYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE
6BETA-HYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE
6BETA-HYDROXY-CARNOSOL
7BETA-ACETOXY-6BETA,9ALPHA-DIHYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE
8,13-EPOXY-LABD-14-EN-11-ONE
9-DEOXYFORSKOHLIN
ALPHA-COPAENEC₁₅H₂₄204.35 Da
ALPHA-FENCHYL-ACETATEC₁₂H₂₀O₂196.29 Da
AROMADENDRENEC₁₅H₂₄204.35 Da
BARBATUSIN
BARBATUSOLC₂₀H₂₈O₂300.4 Da
BETA-BISABOLENEC₁₅H₂₄204.35 Da
BORNEOLC₁₀H₁₈O154.25 Da
BORNEOL-ACETATEC₁₂H₂₀O₂196.29 Da
CALAMENENE-HYDRATE
CARIOCALC₂₀H₂₆O₅346.4 Da
CIS-ALPHA-BERGAMOTENEC₁₅H₂₄204.35 Da
COLEOL
COLEONOLC₂₂H₃₄O₇410.5 Da
COLEONOLS
COLEONS
COLEOSOL
CYCLOBUTATUSIN
DEACETYL-FORSKOHLIN
DEHYDROABIETANEC₂₀H₃₀270.5 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources