Botanical Overview
Cordoncillo (Piper auritum) belongs to the Piperaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. This species belongs to the Piperaceae family, a group of flowering plants.

General Description
Common names include hoja santa (Spanish for ‘sacred leaf’), yerba santa, hierba santa, Mexican pepperleaf, acuyo, tlanepa, anisillo, root beer plant, Vera Cruz pepper, sacred pepper, and juniapa.
Family Context
The Piperaceae family is widely distributed. Notable medicinal members include:
- Betel Pepper — 51 documented uses
- Black Pepper — 46 documented uses
- Cubeb — 33 documented uses
- Matico — 23 documented uses
Geographic Distribution
Cordoncillo has been recorded in 10 countries and territories worldwide, including Belize, Colombia, Costa Rica, Guatemala, Honduras, and others.
Traditional Uses
Cordoncillo has been traditionally used for digestive health and pain and inflammation.
Digestive health.
- Ache(Stomach)
For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.
Pain and inflammation.
- Ache(Head)
For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.
Active Compounds
Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Sterol: cholesterol-like compounds with anti-inflammatory properties
- Alkaloid: nitrogenous compounds with diverse pharmacological activities