Lignum Quassia

Also known as: Nigaki, Shurni

Botanical Overview

Lignum Quassia (Picrasma quassioides) belongs to the Simaroubaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The quassia family (Simaroubaceae) includes trees and shrubs with bitter bark, compound leaves, and small, unisexual flowers. The fruits are typically drupes or samaras. Many species contain quassinoids, intensely bitter compounds with antimalarial and anticancer activity.

General Description

P. ailanthioides) is a species of Picrasma native to temperate regions of southern Asia, from the northeast of Pakistan east along the Himalaya and through East Asia from southern, central and eastern China to Taiwan, Japan and Korea. It is a deciduous shrub or small tree growing to 10–15 m (rarely 20 m) tall with a trunk up to 50 cm diameter. The bark is smooth and dark grey-brown. The leaves are 15–40 cm long, pinnate, with 7–15 leaflets 2. 5–10 cm long and 1. 5–4. 5 cm broad, with a coarsely and irregularly toothed margin. The flowers are green to yellow-green with four or five sepals and petals, produced in cymes 8–15 cm long in mid to late spring. The fruit is an ovoid to globose, red to black drupe 6–7 mm diameter.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Simaroubaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Lignum Quassia has been recorded in 10 countries and territories worldwide, including China, Hong Kong, India, Japan, North Korea, and others.

Traditional Uses

Lignum Quassia has been traditionally used for digestive health, skin and wound care, and fever management.

Digestive health.

  • Stomachic

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Skin and wound care.

  • Itch

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Fever management.

  • Fever

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Active Compounds

Phytochemical research has identified 28 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Terpene: aromatic compounds with anti-inflammatory and antimicrobial properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: China, Hong Kong, India, Japan, North Korea, South Korea, Nepal, Taiwan, United States, Unknown.

Complete Use Records

CategoryCultural Context
FeverAsia, India(Punjab)
InsecticideIndia(Punjab), Japan
ItchElsewhere
PulicideElsewhere
StomachicElsewhere

Complete Chemical Inventory

CompoundFormulaMW
1-ACETYL-BETA-CARBOLINEC₁₃H₁₀N₂O210.23 Da
1-CARBOXY-BETA-CARBOLINE
1-HYDROXYMETHYL-BETA-CARBOLINEC₁₂H₁₀N₂O198.22 Da
3-METHYLCANTHIN-2,6-DIONEC₁₅H₁₀N₂O₂250.25 Da
4,8-DIMETHOXY-1-(2-METHOXYETHYL)-BETA-CARBOLINE
4,8-DIMETHOXY-1-ETHYL-BETA-CARBOLINE
BETA-CARBOLIN-1-YL-4,8-DIMETHOXY-BETA-CARBOLIN-1-YL-ETHYL...
KUMIJIANS
KUSULACTONEC₂₅H₃₄O₉478.5 Da
METHYL-BETA-CARBOLINE-1-CARBOXYLATE
METHYLNIGAKINONEC₁₆H₁₂N₂O₃280.28 Da
NEGAKILACTONE-B
NEOQUASSINC₂₂H₃₀O₆390.5 Da
NIGAKIHEMIACETAL-AC₂₂H₃₄O₇410.5 Da
NIGAKIHEMIACETAL-CC₂₁H₃₂O₆380.5 Da
NIGAKILACTONE-AC₂₁H₃₀O₆378.5 Da
NIGAKILACTONE-CC₂₄H₃₄O₇434.5 Da
NIGAKILACTONE-DC₂₂H₂₈O₆388.5 Da
NIGAKILACTONE-EC₂₄H₃₄O₈450.5 Da
NIGAKILACTONE-FC₂₂H₃₂O₇408.5 Da
NIGAKILACTONE-M,N,H,J,K,L
NIGAKINONEC₁₅H₁₀N₂O₃266.25 Da
PALMITIC-ACIDC₁₆H₃₂O₂256.42 Da
PETROSELINIC-ACIDC₁₈H₃₄O₂282.5 Da
PICRASIDINES
PICRASIN
PICRASIN-A,B,C,D,E,F,G
QUASSINC₂₂H₂₈O₆388.5 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources