Seed On The Leaf

Botanical Overview

Seed On The Leaf (Phyllanthus niruri) is a flowering plant in the Euphorbiaceae family. This plant has earned a place in traditional medicine through its consistent therapeutic benefits, recorded across multiple cultures. The spurge family (Euphorbiaceae) includes an extremely diverse group of plants ranging from small herbs to large trees, many with milky sap that can be irritating or toxic. The flowers are typically small and unisexual, often arranged in distinctive inflorescences. Many species contain diterpene esters and other bioactive compounds.

General Description

It has the common name chanca piedra among numerous others in Spanish.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Euphorbiaceae family is large and globally distributed. Notable medicinal members include:

Geographic Distribution

Seed On The Leaf has been recorded in 10 countries and territories worldwide, including Argentina, Bolivia, Brazil, China, Colombia, and others.

Traditional Uses

Seed On The Leaf has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.

Digestive health.

  • Ache(Stomach)
  • Dysentery
  • Diarrhea
  • Carminative
  • Colic
  • Dyspepsia
  • Laxative
  • Stomachic

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Cough

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Itch

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Active Compounds

Phytochemical research has identified 27 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
  • Saponin: soap-like compounds with immune-modulating activity
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Argentina, Bolivia, Brazil, China, Colombia, Costa Rica, India, Mexico, Paraguay, Venezuela.

Complete Use Records

CategoryCultural Context
FeverBahamas, Brazil, Haiti, Philippines, Puerto Rico
DiureticHaiti, India, Malaya, Samoa
Ache(Stomach)Bahamas, Haiti, Java
DysenteryAfrica, India, Marianas I
GonorrheaGold Coast, India, Java
DiarrheaMalaya, Reunion
ItchMalaya, Marianas I
MalariaDominican Republic, Haiti
CarminativeHaiti
Sting(Caterpillar)Malaya
ColicHaiti
CoughJava
DermatosisMalaya
DigestiveHaiti
DropsyReunion
DyspepsiaAfrica
EmmenagoguePhilippines
FluBahamas
KidneyBrazil
LaxativeBahamas
MedicineSudan
PiscicideMalaya
PoulticeSamoa
RectitisMarianas I
RenosisMalaya
StomachicHaiti
Tumor(Abdomen)India
VaginitisMarianas I
VertigoMalaya
BlennorrhagiaReunion

Complete Chemical Inventory

CompoundFormulaMW
3,5,7-TRIHYDROXYFLAVONAL-4'-O-ALPHA-L-(-)-RHAMNOPYRANOSIDE
4-METHOXY-NORSECURININE
4-METHOXY-SECURININE
5,3',4'-TRIHYDROXYFLAVONONE-7-O-ALPHA-L-(-)-RHAMNOPYRANOSIDE
ASTRAGALINC₂₁H₂₀O₁₁448.4 Da
BREVIFOLIN-CARBOXYLIC-ACIDC₁₃H₈O₈292.20 Da
CYMENEC₁₀H₁₄134.22 Da
HYPOPHYLLANTHINE
LIMONENEC₁₀H₁₆136.23 Da
LINTETRALINC₂₃H₂₈O₆400.5 Da
LUPA-20(29)-ENE-3-BETA-OL
LUPA-20(29)-ENE-3-BETA-OL-ACETATE
LUPEOLC₃₀H₅₀O426.7 Da
METHYL-SALICYLATEC₈H₈O₃152.15 Da
NIRANTHINC₂₄H₃₂O₇432.5 Da
NIRTETRALINC₂₄H₃₀O₇430.5 Da
NIRURETIN
NIRURINC₃₂H₄₀O₁₅664.6 Da
PHYLLANTHINC₂₄H₃₄O₆418.5 Da
PHYLLOCHRYSINEC₁₃H₁₅NO₂217.26 Da
PHYLTETRALINC₂₄H₃₂O₆416.5 Da
QUERCETINC₁₅H₁₀O₇302.23 Da
QUERCETIN-HETEROSIDE
QUERCETOLC₁₅H₁₀O₇302.23 Da
QUERCITRINC₂₁H₂₀O₁₁448.4 Da
RUTINC₂₇H₃₀O₁₆610.5 Da
SAPONINSC₅₅H₈₆O₂₄1131.3 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources