Phyllanthus amarus

Botanical Overview

Phyllanthus amarus belongs to the Euphorbiaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The spurge family (Euphorbiaceae) includes an extremely diverse group of plants ranging from small herbs to large trees, many with milky sap that can be irritating or toxic. The flowers are typically small and unisexual, often arranged in distinctive inflorescences. Many species contain diterpene esters and other bioactive compounds.

General Description

Commons names for this plant include gale of the wind, carry me seed, seed on the leaf, pick-a-back, stonebreaker, and dukung anak (Malay).

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Euphorbiaceae family is large and globally distributed. Notable medicinal members include:

Geographic Distribution

Phyllanthus amarus has been recorded in 10 countries and territories worldwide, including Australia, Benin, Brazil, Cameroon, India, and others.

Traditional Uses

Phyllanthus amarus has been traditionally used for urinary tract health, fever management, and reproductive health, among other applications.

Urinary tract health.

  • Diuretic

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Fever management.

  • Malaria

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Reproductive health.

  • Venereal

In traditional contexts, reproductive health applications typically involve internal preparations such as teas or decoctions. The herb may be taken at specific times during the menstrual cycle.

Active Compounds

Phytochemical research has identified 23 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Phenolic: antioxidant compounds that neutralize free radicals
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
  • Tannin: astringent compounds that tighten tissues and resist infection
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Australia, Benin, Brazil, Cameroon, India, Mexico, French Polynesia, Reunion, Taiwan, United States.

Complete Use Records

CategoryCultural Context
DiabetesHaiti
MalariaHaiti
VenerealTrinidad
PiscicidePolynesia
DigestiveHaiti
OliguriaTrinidad
DiureticHaiti

Complete Chemical Inventory

CompoundFormulaMW
1-6-DI-GALLOYL-GLUCOPYRANOSE
4-O-GALLOYL-QUINIC ACID
AMARIINC₄₁H₂₈O₂₈968.6 Da
AMARIINIC ACID
AMARULONE
CORILAGINC₂₇H₂₂O₁₈634.5 Da
ELAEOCARPUSIN
EPIBUBBIALINEC₁₂H₁₅NO₃221.25 Da
FUROSINC₂₇H₂₂O₁₉650.5 Da
GALLIC-ACIDC₇H₆O₅170.12 Da
GALLOCATECHINC₁₅H₁₄O₇306.27 Da
GERANIINC₄₁H₂₈O₂₇952.6 Da
GERANIINIC ACID
HYPOPHYLLANTHINC₂₄H₃₀O₇430.5 Da
ISOBUBBIALINEC₁₂H₁₅NO₃221.25 Da
ISOQUERCITRINC₂₁H₂₀O₁₂464.4 Da
NORSECURININEC₁₂H₁₃NO₂203.24 Da
PHYLLANTHINC₂₄H₃₄O₆418.5 Da
PHYLLANTHINEC₁₄H₁₇NO₃247.29 Da
PHYLLANTHUSIIN D
REPANDUSINIC ACID BC₄₈H₃₄O₃₃1138.8 Da
RUTINC₂₇H₃₀O₁₆610.5 Da
SECURININEC₁₃H₁₅NO₂217.26 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources