European Butterbur

Botanical Overview

European Butterbur (Petasites hybridus) belongs to the Asteraceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The daisy family (Asteraceae) is one of the largest plant families, characterized by composite flower heads (capitula) that contain many small florets surrounded by bracts. Plants range from tiny alpine herbs to large tropical trees. The family includes many medicinally important species with bitter compounds and essential oils.

General Description

Although used over centuries in traditional medicine to treat various disorders, there are no approved medical uses, but it is sold as a dietary supplement. Concerns about the potential toxic effects of pyrrolizidine alkaloids in butterbur limit its use in human and animal studies.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Asteraceae family is extremely large and diverse. Notable medicinal members include:

Traditional Uses

European Butterbur has been traditionally used for immune system support.

Immune system support.

  • Tumor

Immune support involves taking the herb as a decoction or tincture over extended periods. The active compounds stimulate immune cell activity and provide antimicrobial protection.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Complete Use Records

CategoryCultural Context
TumorBelgium

Complete Chemical Inventory

CompoundFormulaMW
(Z)-3-METHYLTHIOACRYLOYLISOPETASYL-ESTER
2-ANGELOYLOXY-9-OXO-10-ALPHA-FURANOEREMOPHILANE
3-(METHYL-THIO)-ACRYLOYL-TRANS-PETASOL
3-DEOXYNEOPETASOL
3-METHYL-CROTONOYLISOPETASOL
3-METHYL-CROTONOYLNEOPETASOL
3-METHYL-CROTONYLPETASOL
8,12-DIMETHOXYDIHYDROFUROEREMOPHILANE
9-HYDROXYFUROEREMOPHILANE
ALPHA-HUMULENEC₁₅H₂₄204.35 Da
ANGELIC-ACIDC₅H₈O₂100.12 Da
ANGELICOYLISOPETASOL
ANGELICOYLNEOPETASOL
ANGELICOYLPETASIN
ARACHIC-ACIDC₂₀H₄₀O₂312.5 Da
ASTRAGALINC₂₁H₂₀O₁₁448.4 Da
BAKKENOLIDEC₁₅H₂₂O₂234.33 Da
BAUERENOLC₃₀H₅₀O426.7 Da
BEHENIC-ACIDC₂₂H₄₄O₂340.6 Da
BETA-BISABOLENEC₁₅H₂₄204.35 Da
BETA-ELEMENEC₁₅H₂₄204.35 Da
BETA-HUMULENEC₁₅H₂₄204.35 Da
BETA-SANTALENEC₁₅H₂₄204.35 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CAMPESTEROLC₂₈H₄₈O400.7 Da
CHOLINEC₅H₁₄NO+104.17 Da
CIS-2-METHYL-2-BUTENOYL-ESTER-NEOPETASOL
CIS-2-METHYL-2-BUTYENYL-3-DEOXY-13-PETASYL-ESTER
CIS-2-METHYL-2-BUTYENYLNEOPETASYL-ESTER
CIS-2-METHYL-2-BUTYENYLPETASYL-ESTER

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources