Botanical Overview
Granadilla (Passiflora quadrangularis) is a flowering plant in the Passifloraceae family. Traditional medicine systems have documented several valuable applications for this species, supported by its observed therapeutic effects. This species belongs to the Passifloraceae family, a group of flowering plants.

General Description
It produces the largest fruit of any species within the genus Passiflora. It is a perennial climber native to the Neotropics.
Family Context
The Passifloraceae family is widely distributed. Notable medicinal members include:
- Manzana de Mayo — 20 documented uses
- Granadilla Cimarrona — 19 documented uses
- Maracuya — 9 documented uses
Geographic Distribution
Granadilla has been recorded in 10 countries and territories worldwide, including Brazil, Colombia, Costa Rica, Ecuador, Jamaica, and others.
Traditional Uses
Granadilla has been traditionally used for pain and inflammation, nervous system disorders, and cardiovascular health, among other applications.
Pain and inflammation.
- Neuralgia
- Arthritis
- Inflammation
For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.
Nervous system disorders.
- Sedative
- Narcotic
Nervous system support involves taking the herb as a warm tea, often in the evening or before bed. The calming compounds interact with neurotransmitter systems to promote relaxation and restful sleep.
Cardiovascular health.
- Hypertension
Active Compounds
Phytochemical research has identified 17 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Alkaloid: nitrogenous compounds with diverse pharmacological activities