Botanical Overview
Manzana de Mayo (Passiflora incarnata) is a flowering plant in the Passifloraceae family. This plant has earned a place in traditional medicine through its consistent therapeutic benefits, recorded across multiple cultures. This species belongs to the Passifloraceae family, a group of flowering plants.

General Description
A member of the passionflower genus Passiflora, the maypop has large, intricate flowers with prominent styles and stamens. One of the hardiest species of passionflower, it is both found as a wildflower in the southern United States and in cultivation for its edible fruit and striking bluish purple blooms.
Family Context
The Passifloraceae family is widely distributed. Notable medicinal members include:
- Granadilla — 22 documented uses
- Granadilla Cimarrona — 19 documented uses
- Maracuya — 9 documented uses
Geographic Distribution
Manzana de Mayo has been recorded in 10 countries and territories worldwide, including Brazil, Canada, Spain, India, Italy, and others.
Traditional Uses
Manzana de Mayo has been traditionally used for digestive health, skin and wound care, and pain and inflammation, among other applications.
Digestive health.
- Diarrhea
For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.
Skin and wound care.
- Burn
- Skin
- Eruption
For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.
Pain and inflammation.
- Neuralgia
For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.
Active Compounds
Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Flavonoid: antioxidant compounds that protect cells from oxidative damage
- Alkaloid: nitrogenous compounds with diverse pharmacological activities