Manzana de Mayo

Also known as: Mayapple, Passionflower

Botanical Overview

Manzana de Mayo (Passiflora incarnata) is a flowering plant in the Passifloraceae family. This plant has earned a place in traditional medicine through its consistent therapeutic benefits, recorded across multiple cultures. This species belongs to the Passifloraceae family, a group of flowering plants.

General Description

A member of the passionflower genus Passiflora, the maypop has large, intricate flowers with prominent styles and stamens. One of the hardiest species of passionflower, it is both found as a wildflower in the southern United States and in cultivation for its edible fruit and striking bluish purple blooms.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Passifloraceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Manzana de Mayo has been recorded in 10 countries and territories worldwide, including Brazil, Canada, Spain, India, Italy, and others.

Traditional Uses

Manzana de Mayo has been traditionally used for digestive health, skin and wound care, and pain and inflammation, among other applications.

Digestive health.

  • Diarrhea

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Skin and wound care.

  • Burn
  • Skin
  • Eruption

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Pain and inflammation.

  • Neuralgia

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Narcotic. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Brazil, Canada, Spain, India, Italy, Madagascar, Mexico, New Caledonia, United States, Unknown.

Complete Use Records

CategoryCultural Context
InsomniaElsewhere, Iraq, Turkey, US
NarcoticElsewhere, Iraq, Turkey
NeuralgiaElsewhere, Turkey, US
DysmenorrheaTurkey, US
EpilepsyElsewhere, Turkey
SedativeElsewhere, Turkey
SpasmElsewhere, Turkey
AphrodisiacUS
BurnUS
MedicineUS(Appalachia)
MorphinismElsewhere
PerfumeBermuda
SkinUS
SoporificTurkey
DiarrheaUS
PilesUS
CyanogeneticUS
EyeUS
NeurosisTurkey
EruptionUS

Complete Chemical Inventory

CompoundFormulaMW
ALKALOIDS
ALPHA-ALANINEC₃H₇NO₂89.09 Da
APIGENINC₁₅H₁₀O₅270.24 Da
ASCORBIC-ACIDC₆H₈O₆176.12 Da
ASH
BETA-CAROTENEC₄₀H₅₆536.9 Da
BUTYRIC-ACIDC₄H₈O₂88.11 Da
CALCIUMCa40.08 Da
CAMPHEROLC₁₅H₁₀O₆286.24 Da
CARBOHYDRATES
CHROMIUMCr51.996 Da
COBALTCo58.93319 Da
D-FRUCTOSEC₆H₁₂O₆180.16 Da
D-GLUCOSEC₆H₁₂O₆180.16 Da
ETHYL-MALTOLC₇H₈O₃140.14 Da
FATC₁₆H₃₂O₂256.42 Da
FIBER
FIBER(CRUDE)
FIBER(DIETARY)
FLAVONOIDS
FORMIC-ACIDCH₂O₂46.025 Da
GLUTAMINEC₅H₁₀N₂O₃146.14 Da
GUM
GYNOCARDINC₁₂H₁₇NO₈303.26 Da
HARMALINEC₁₃H₁₄N₂O214.26 Da
HARMALOLC₁₂H₁₂N₂O200.24 Da
HARMANEC₁₂H₁₀N₂182.22 Da
HARMINEC₁₃H₁₂N₂O212.25 Da
HARMOLC₁₂H₁₀N₂O198.22 Da
HOMOORIENTINC₂₁H₂₀O₁₁448.4 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources