Japanese Ginseng

Botanical Overview

Japanese Ginseng (Panax japonicus) is a species in the Araliaceae family. The ivy family (Araliaceae) includes trees, shrubs, and climbers with alternate, often compound leaves and small flowers arranged in umbels. The fruits are typically fleshy berries. Many species produce triterpenoid saponins with adaptogenic and anti-inflammatory properties. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 30 compounds in this species, suggesting potential medicinal value.

General Description

It is found throughout Japan and Korea, and is also said to be endangered in China. Panax japonicus sees some use in Japanese Kampo medicine and traditional Chinese medicine. Like other ginsengs, it contains a number of ginsenosides. There is no English-language literature on its cultivation, though Baeg et al. (2013) lists it among cultivated ginseng species. There is, however, a considerable volume of Chinese literature on its cultivation under the name Zhújiéshēn.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Araliaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Japanese Ginseng has been recorded in 10 countries and territories worldwide, including Australia, China, Japan, South Korea, Myanmar, and others.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Saponin: soap-like compounds with immune-modulating activity

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Australia, China, Japan, South Korea, Myanmar, Norway, Nepal, Poland, Vietnam, Unknown.

Complete Chemical Inventory

CompoundFormulaMW
ARABINOSEC₅H₁₀O₅150.13 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CALCIUMCa40.08 Da
CAMPESTEROLC₂₈H₄₈O400.7 Da
CAMPESTEROL-6'-LINOLENYLGLUCOSIDE
CAMPESTEROL-6'-LINOYLGLUCOSIDE
CAMPESTEROL-6'-OLEYLGLUCOSIDE
CAMPESTEROL-6'-PALMITYLGLUCOSIDE
CAMPESTEROL-6'-STEARYLGLUCOSIDE
CHIKUSETSUSAPONIN-I-A
CHIKUSETSUSAPONIN-I-B
CHIKUSETSUSAPONIN-IIIC₄₇H₈₀O₁₇917.1 Da
CHIKUSETSUSAPONIN-IVC₄₇H₇₄O₁₈927.1 Da
CHIKUSETSUSAPONIN-IV-A
CHIKUSETSUSAPONIN-L-10
CHIKUSETSUSAPONIN-L-5
CHIKUSETSUSAPONIN-L-9A
CHIKUSETSUSAPONIN-LN-4
CHIKUSETSUSAPONIN-LT-5
CHIKUSETSUSAPONIN-LT-8
CHIKUSETSUSAPONIN-VC₄₈H₇₆O₁₉957.1 Da
COPPERCu63.55 Da
GINSENOSIDE-F-1
GINSENOSIDE-R-O
GINSENOSIDE-RDC₄₈H₈₂O₁₈947.2 Da
GINSENOSIDE-RG-2
GLUCOSEC₆H₁₂O₆180.16 Da
GLUCURONIC-ACIDC₆H₁₀O₇194.14 Da
IRONFe55.84 Da
MAGNESIUMMg24.305 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources