Horehound

Also known as: White Horehound

Botanical Overview

Horehound (Marrubium vulgare) is a flowering plant in the Lamiaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The mint family (Lamiaceae) includes aromatic herbs and shrubs with square stems, opposite leaves, and two-lipped flowers. Many species produce essential oils in glandular trichomes on their leaves and stems. This family is one of the most important sources of culinary and medicinal herbs worldwide.

Family Context

The Lamiaceae family is large and widely distributed. Notable medicinal members include:

  • Basil — 86 documented uses
  • Rosemary — 60 documented uses
  • Agbo — 54 documented uses
  • Sage — 49 documented uses

Geographic Distribution

Horehound has been recorded in 10 countries and territories worldwide, including Australia, Germany, Spain, France, United Kingdom, and others.

Traditional Uses

Horehound has been traditionally used for digestive health, respiratory conditions, and urinary tract health, among other applications.

Digestive health.

  • Laxative
  • Carminative
  • Stomachic

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Cold
  • Cough
  • Expectorant
  • Asthma
  • Bronchitis
  • Catarrh

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Urinary tract health.

  • Diuretic

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Australia, Germany, Spain, France, United Kingdom, Mexico, Netherlands, Portugal, Sweden, United States.

Complete Use Records

CategoryCultural Context
FeverElsewhere, Mexico, Spain, Turkey
ColdElsewhere, Europe, US
CoughElsewhere, Europe, US(Appalachia)
DiureticElsewhere, Mexico, Turkey
ExpectorantElsewhere, Europe, Turkey
LaxativeElsewhere, Europe, US
TonicElsewhere, Turkey, US
DebilityEurope, US
Sore(Throat)Europe, Iraq
TumorMexico, UK
AlterativeTurkey
AsthmaUS
BiliousMexico
BronchitisTurkey
CarminativeTurkey
CatarrhMexico
CholeraElsewhere
DysmenorrheaUS
ExtrasystoleElsewhere
HeartKurdistan
HepatitisMexico
HypertensionElsewhere
LarvicideMexico
LiqueurUS
MedicineUS(Appalachia)
PalpitationIraq
PertussisMexico
SpasmMexico
StomachicTurkey
SudorificEurope

Complete Chemical Inventory

CompoundFormulaMW
13(R)-PREMARRUBIIN
13(S)-PREMARRUBIIN
2-(OMEGA-1)-METHYLALKANES
2-METHYL-ALKANES
3-(OMEGA-9)-METHYLALKANES
3-METHYL-ALKANES
ALPHA-PINENEC₁₀H₁₆136.23 Da
ALPHA-TERPINOLENEC₁₀H₁₆136.23 Da
APIGENINC₁₅H₁₀O₅270.24 Da
APIGENIN-7-(2-GLUCOSYL-LACTATE)
APIGENIN-7-(2-GLUCURONOSYL-LACTATE)
APIGENIN-7-LACTATEC₁₈H₁₄O₇342.3 Da
APIGENIN-7-O-(6'-P-COUMAROYL-GLUCOSIDE)
APIGENIN-7-O-GLYCOSIDEC₂₁H₂₀O₁₀432.4 Da
ASCORBIC-ACIDC₆H₈O₆176.12 Da
BETA-ELEMENEC₁₅H₂₄204.35 Da
BETA-PINENEC₁₀H₁₆136.23 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
BETA-SITOSTEROL-BETA-GLUCOSIDE
BETONICINEC₇H₁₃NO₃159.18 Da
BISABOLOLC₁₅H₂₆O222.37 Da
CAFFEIC-ACIDC₉H₈O₄180.16 Da
CAMPHENEC₁₀H₁₆136.23 Da
CHLOROGENIC-ACIDC₁₆H₁₈O₉354.31 Da
CHOLINEC₅H₁₄NO+104.17 Da
CHRYSOERIOLC₁₆H₁₂O₆300.26 Da
COSMOSIINC₂₁H₂₀O₁₀432.4 Da
CRYPTOCHLOROGENIC-ACIDC₁₆H₁₈O₉354.31 Da
CYNAROSIDEC₂₁H₂₀O₁₁448.4 Da
DIHYDROPEREGRININ

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources