Creeping Barberry

Also known as: Oregon Barberry, Oregon Grape-Holly, Oregon Grape

Botanical Overview

Creeping Barberry (Mahonia repens) belongs to the Berberidaceae family. Limited but reliable traditional records indicate this plant has recognized medicinal applications in one or more healing traditions. The barberry family (Berberidaceae) includes shrubs and herbs with alternate or basal leaves and yellow wood or roots due to alkaloid content. The flowers have six sepals and six petals arranged in whorls, and the fruits are berries or capsules. Many species produce isoquinoline alkaloids like berberine with antimicrobial activity.

Family Context

The Berberidaceae family is widely distributed in temperate regions. Notable medicinal members include:

Geographic Distribution

Creeping Barberry has been recorded in 10 countries and territories worldwide, including Belarus, Canada, Germany, Estonia, United Kingdom, and others.

Traditional Uses

Creeping Barberry has been traditionally used for urinary tract health, fever management, and metabolic and nutritional health.

Urinary tract health.

  • Kidney

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Fever management.

  • Fever

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Metabolic and nutritional health.

  • Tonic

Metabolic applications include consuming the plant as a food, fresh juice, or herbal infusion. Regular use supports the body’s natural metabolic processes and nutritional status.

Active Compounds

Phytochemical research has identified 17 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Belarus, Canada, Germany, Estonia, United Kingdom, Norway, Poland, Russia, United States, Unknown.

Complete Use Records

CategoryCultural Context
FeverUS
KidneyUS
TonicUS
IntoxicantUS

Complete Chemical Inventory

CompoundFormulaMW
(+)-CORYDINEC₂₀H₂₃NO₄341.4 Da
(+)-GLAUCINEC₂₁H₂₅NO₄355.4 Da
(+)-ISOCORYDINEC₂₀H₂₃NO₄341.4 Da
5'-METHOXYHYDNOCARPINC₂₆H₂₂O₁₀494.4 Da
BERBERINEC₂₀H₁₈NO₄+336.4 Da
CHLOROGENIC-ACIDC₁₆H₁₈O₉354.31 Da
COLUMBAMINEC₂₀H₂₀NO₄+338.4 Da
JATRORRHIZINEC₂₀H₂₀NO₄+338.4 Da
MAGNOFLORINEC₂₀H₂₄NO₄+342.4 Da
OBABERINEC₃₈H₄₂N₂O₆622.7 Da
OBAMEGINEC₃₆H₃₈N₂O₆594.7 Da
OXYACANTHINEC₃₇H₄₀N₂O₆608.7 Da
PALMATINEC₂₁H₂₂NO₄+352.4 Da
SUCROSEC₁₂H₂₂O₁₁342.30 Da
SYRINGARESINOLC₂₂H₂₆O₈418.4 Da
THALIPORPHINEC₂₀H₂₃NO₄341.4 Da
THALRUGOSINEC₃₇H₄₀N₂O₆608.7 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources