Oregon Barberry

Also known as: Oregon Grape-Holly, Oregon Grape, Water Holly

Botanical Overview

Oregon Barberry (Mahonia nervosa) is a species in the Berberidaceae family. The barberry family (Berberidaceae) includes shrubs and herbs with alternate or basal leaves and yellow wood or roots due to alkaloid content. The flowers have six sepals and six petals arranged in whorls, and the fruits are berries or capsules. Many species produce isoquinoline alkaloids like berberine with antimicrobial activity. Phytochemical data for this species are limited at present.

Family Context

The Berberidaceae family is widely distributed in temperate regions. Notable medicinal members include:

Geographic Distribution

Oregon Barberry has been recorded in 10 countries and territories worldwide, including Canada, Colombia, Denmark, Spain, South Korea, and others.

Active Compounds

Phytochemical research has identified 1 compound in this species: berberine.

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Canada, Colombia, Denmark, Spain, South Korea, Mexico, Norway, Poland, United States, Unknown.

Complete Chemical Inventory

CompoundFormulaMW
BERBERINEC₂₀H₁₈NO₄+336.4 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources