Botanical Overview
Peyote (Lophophora williamsii) is a flowering plant in the Cactaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The cactus family (Cactaceae) includes succulent plants with thick, fleshy stems modified for water storage and spines instead of leaves. The flowers are typically large, showy, and short-lived with numerous petals and stamens. Many species produce alkaloids and have traditional medicinal uses.

General Description
Peyote is a Spanish word derived from the Nahuatl peyōtl, meaning “caterpillar cocoon”, from a root peyōni, “to glisten”.
Family Context
The Cactaceae family is widely distributed. Notable medicinal members include:
- Indian Fig — 19 documented uses
- Night-Blooming Cereus — 9 documented uses
- Night-Blooming Cereus — 3 documented uses
- Night-Blooming Cereus — 3 documented uses
Geographic Distribution
Peyote has been recorded in 10 countries and territories worldwide, including Belgium, Germany, Spain, France, Japan, and others.
Traditional Uses
Peyote has been traditionally used for pain and inflammation, nervous system disorders, and fever management, among other applications.
Pain and inflammation.
- Ache(Head)
- Anodyne
- Arthritis
- Rheumatism
For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.
Nervous system disorders.
- Sedative
- Narcotic
Nervous system support involves taking the herb as a warm tea, often in the evening or before bed. The calming compounds interact with neurotransmitter systems to promote relaxation and restful sleep.
Fever management.
- Fever
Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.
Active Compounds
Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Terpene: aromatic compounds with anti-inflammatory and antimicrobial properties
- Alkaloid: nitrogenous compounds with diverse pharmacological activities