Malabar Nut

Botanical Overview

Malabar Nut (Justicia adhatoda) belongs to the Acanthaceae family. Limited but reliable traditional records indicate this plant has recognized medicinal applications in one or more healing traditions. The acanthus family (Acanthaceae) includes herbs and shrubs with opposite leaves and showy, two-lipped flowers with prominent bracts. The fruits are explosive capsules that eject seeds when mature. Many species contain alkaloids and have traditional medicinal uses.

General Description

Adathoda means ‘untouched by goats’ in Tamil. The name derives from the fact that animals like goats do not eat this plant due to its extreme bitter taste. The plant’s native range is Afghanistan, the Indian subcontinent (Bangladesh, India, Pakistan, Nepal and Sri Lanka), Laos, Myanmar and Vietnam. It has been introduced elsewhere. It is used as a traditional medicinal plant.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Acanthaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Malabar Nut has been recorded in 10 countries and territories worldwide, including Bhutan, China, Spain, Indonesia, India, and others.

Traditional Uses

Malabar Nut has been traditionally used for respiratory conditions, nervous system disorders, and fever management, among other applications.

Respiratory conditions.

  • Bronchitis
  • Cough
  • Expectorant
  • Asthma

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Nervous system disorders.

  • Spasm

Nervous system support involves taking the herb as a warm tea, often in the evening or before bed. The calming compounds interact with neurotransmitter systems to promote relaxation and restful sleep.

Fever management.

  • Fever

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Bhutan, China, Spain, Indonesia, India, Sri Lanka, Nepal, Pakistan, United States, Unknown.

Complete Use Records

CategoryCultural Context
AlterativeFrench
Tumor(Abdomen)India
BronchitisIndia(Santal)
TuberculosisIndia(Santal)
CoughIndia(Santal)
ExpectorantTurkey
AsthmaIndia
SpasmEnglish
FeverItalian

Complete Chemical Inventory

CompoundFormulaMW
1,2,3,9-TETRAHYDRO-5-METHOXYPYRROLO-(2,1-B)-QUINAZOLINE-3-OL
2',4-DIHYDROXYCHALCONE-4-GLUCOSIDE
6-HYDROXYPEGANINE
9-ACETAMIDO-3,4-DIHYDROPYRIDO-(3,4-B)-INDOLEC₁₃H₁₃N₃O227.26 Da
ADHATODIC-ACID
ADHATODINE
ADHATONINE
ALKALOIDS
ANISOTINEC₂₀H₁₉N₃O₃349.4 Da
ANISOTININE
ARACHIDIC-ACIDC₂₀H₄₀O₂312.5 Da
BEHENIC-ACIDC₂₂H₄₄O₂340.6 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
BETA-SITOSTEROL-BETA-D-GLUCOSIDEC₃₅H₆₀O₆576.8 Da
BETAINEC₅H₁₁NO₂117.15 Da
CEROTIC-ACIDC₂₆H₅₂O₂396.7 Da
DEOXYVASCINONE
FATC₁₆H₃₂O₂256.42 Da
LIGNOCERIC-ACIDC₂₄H₄₈O₂368.6 Da
LINOLEIC-ACIDC₁₈H₃₂O₂280.4 Da
O-ETHYL-ALPHA-D-GALACTOSIDE
OLEIC-ACIDC₁₈H₃₄O₂282.5 Da
OSCINEC₈H₁₃NO₂155.19 Da
PEGANINEC₁₁H₁₂N₂O188.23 Da
RAAC₁₂H₂₃NO₁₀S₃437.5 Da
VASAKIN
VASICINEC₁₁H₁₂N₂O188.23 Da
VASICININE
VASICINOLC₁₁H₁₂N₂O₂204.22 Da
VASICINONEC₁₁H₁₀N₂O₂202.21 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources