Henbane

Botanical Overview

Henbane (Hyoscyamus niger) is a flowering plant in the Solanaceae family. Traditional medicine systems have documented several valuable applications for this species, supported by its observed therapeutic effects. The nightshade family (Solanaceae) includes herbs, shrubs, and small trees with alternate leaves and star-shaped or trumpet-shaped flowers. The fruits are typically berries or capsules. Many species produce potent alkaloids including tropanes, solanines, and nicotine, making this family both medicinally valuable and potentially toxic.

General Description

Henbane is native to temperate Europe and Siberia, and naturalised in Great Britain and Ireland.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Solanaceae family is widely distributed worldwide. Notable medicinal members include:

Geographic Distribution

Henbane has been recorded in 10 countries and territories worldwide, including Czech Republic, Germany, Spain, France, United Kingdom, and others.

Traditional Uses

Henbane has been traditionally used for respiratory conditions, urinary tract health, and pain and inflammation, among other applications.

Respiratory conditions.

  • Asthma
  • Cough

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Urinary tract health.

  • Cystitis

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Pain and inflammation.

  • Anodyne
  • Gout

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Coumarin: aromatic compounds with anticoagulant and anti-inflammatory effects
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Toxicity warning: Contains tropane alkaloids. Highly toxic. Traditional records: This plant has documented uses including Narcotic, Poison. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Czech Republic, Germany, Spain, France, United Kingdom, Netherlands, Russia, Sweden, Ukraine, United States.

Complete Use Records

CategoryCultural Context
NarcoticChina, Elsewhere, Nepal, Turkey
PoisonChina, India, Turkey, US
AnodyneChinese, Elsewhere, Turkey
AsthmaChina, Elsewhere, Nepal
MydriaticElsewhere, Iraq, Turkey
SedativeElsewhere, Nepal, Turkey
SpasmChina, Elsewhere, Iraq
AnalgesicChina, Elsewhere
CancerIndia, US
HypnoticElsewhere, Turkey
ParasympatholyticElsewhere, Iraq
PertussisChina, Elsewhere
Ache(Tooth)China, India
TumorItaly, UK
AlcoholismIraq
AnaphrodisiacIraq
AntispasmodicChinese
CatharticElsewhere
CNS depressantIraq
CoughChina
CycloplegicIraq
CystitisIraq
DeliriumIraq
DiabetesIndia
EpilepsyChina
EyeElsewhere
FumitoryNiger
GastrospasmChina
GonorrheaIraq
GoutIndia

Complete Chemical Inventory

CompoundFormulaMW
ALKALOIDS
APOATROPINEC₁₇H₂₁NO₂271.35 Da
ARSENICAs74.92159 Da
ATROPINEC₁₇H₂₃NO₃289.4 Da
ATROSCINEC₁₇H₂₁NO₄303.35 Da
BIMETHYLAMINE
CALCIUMCa40.08 Da
CHLOROGENIC-ACIDC₁₆H₁₈O₉354.31 Da
CHOLINEC₅H₁₄NO+104.17 Da
COPPERCu63.55 Da
COUMARINC₉H₆O₂146.14 Da
CUSCOHYGRINE
ESCULETINC₉H₆O₄178.14 Da
FATC₁₆H₃₂O₂256.42 Da
GABAC₄H₉NO₂103.12 Da
GUM
HYOSCYAMINEC₁₇H₂₃NO₃289.4 Da
HYOSCYPICRIN
IRONFe55.84 Da
KAEMPFEROL-3-DIGLYCOSIDE
LINOLEIC-ACIDC₁₈H₃₂O₂280.4 Da
MAGNESIUMMg24.305 Da
MANGANESEMn54.93804 Da
METHYL-PYROLLIDINE
METHYL-PYRROLINE
MUCILAGE
MYRISTIC-ACIDC₁₄H₂₈O₂228.37 Da
OLEIC-ACIDC₁₈H₃₄O₂282.5 Da
PALMITIC-ACIDC₁₆H₃₂O₂256.42 Da
PHYTOSTEROLS

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources