Cutleaf Clubmoss

Botanical Overview

Cutleaf Clubmoss (Huperzia spp) is a species in the Lycopodiaceae family. The clubmoss family (Lycopodiaceae) includes evergreen, moss-like plants with creeping stems and upright branches covered in small, scale-like leaves. These ancient plants reproduce by spores rather than seeds. Several species produce alkaloids used in traditional medicine and as sources of clubmoss powder. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 30 compounds in this species, suggesting potential medicinal value.

Family Context

The Lycopodiaceae family is widely distributed. Notable medicinal members include:

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Additional phytochemical investigation could identify novel bioactive compounds in this plant.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Complete Chemical Inventory

CompoundFormulaMW
16-OXOLYCOCLAVINOL
16-OXOSERRATENETRIOL
4-HYDROXY-4-METHYL-GLUTAMIC-ACID
ACRIFOLINEC₁₆H₂₃NO₂261.36 Da
ALKALOIDS
ALPHA-OBSCURINEC₁₇H₂₆N₂O274.4 Da
ASPARAGINEC₄H₈N₂O₃132.12 Da
BETA-OBSCURINEC₁₇H₂₄N₂O272.4 Da
DEACETYLFAWCETTINE
FERULIC-ACIDC₁₀H₁₀O₄194.18 Da
GLUTAMIC-ACIDC₅H₉NO₄147.13 Da
HUPERZINE-AC₁₅H₁₈N₂O242.32 Da
HUPERZINE-BC₁₆H₂₀N₂O256.34 Da
LEUCINEC₆H₁₃NO₂131.17 Da
LYCOBERGINE
LYCODOLINEC₁₆H₂₅NO₂263.37 Da
LYCOPODINEC₁₆H₂₅NO247.38 Da
LYCOSERRAMINE
LYCOSERRINE
LYCOTHUINE
NICOTINEC₁₀H₁₄N₂162.23 Da
PSEUDOSELAGINEC₁₆H₂₅NO₂263.37 Da
QUERCETIN-GLYCOSIDEC₂₇H₃₀O₁₆610.5 Da
SELAGINEC₁₅H₁₈N₂O242.32 Da
SERRAT-14-ENE-3BETA,21ALPHA,24-TRIOL
SERRAT-14-ENE-3BETA,21ALPHA-DIOLC₃₀H₅₀O₂442.7 Da
SERRAT-14-ENE-3BETA,21BETA-DIOL
SERRATENDIOL
SERRATIDINEC₁₆H₂₃NO₂261.36 Da
SERRATINIDINE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources