American Pennyroyal

Botanical Overview

American Pennyroyal (Hedeoma pulegioides) belongs to the Lamiaceae family. Limited but reliable traditional records indicate this plant has recognized medicinal applications in one or more healing traditions. The mint family (Lamiaceae) includes aromatic herbs and shrubs with square stems, opposite leaves, and two-lipped flowers. Many species produce essential oils in glandular trichomes on their leaves and stems. This family is one of the most important sources of culinary and medicinal herbs worldwide.

General Description

Hedeoma pulegioides, also known as pennyrile, American pennyroyal, or American false pennyroyal, is a species of Hedeoma native to eastern North America, from Nova Scotia and southern Ontario west to Minnesota and South Dakota, and south to northern Georgia and Arkansas.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Lamiaceae family is large and widely distributed. Notable medicinal members include:

  • Basil — 86 documented uses
  • Rosemary — 60 documented uses
  • Agbo — 54 documented uses
  • Sage — 49 documented uses

Geographic Distribution

American Pennyroyal has been recorded in 7 countries and territories worldwide, including Brazil, Canada, Italy, Mexico, Sweden, and others.

Traditional Uses

American Pennyroyal has been traditionally used for digestive health, respiratory conditions, and pain and inflammation, among other applications.

Digestive health.

  • Colic
  • Carminative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Cold
  • Pneumonia

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Pain and inflammation.

  • Ache(Head)

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Abortifacient. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Brazil, Canada, Italy, Mexico, Sweden, United States, Unknown.

Complete Use Records

CategoryCultural Context
EmmenagogueDutch, US
AbortifacientGerman
Ache(Head)US(Amerindian)
ColdUS
MedicineUS(Appalachia)
PertussisUS(Amerindian)
PneumoniaUS(Appalachia)
SudorificUS
ColicEnglish
MeaslesUS(Amerindian)
StimulantEnglish
TeaUS(Amerindian)
CarminativeFrench

Complete Chemical Inventory

CompoundFormulaMW
(+)-ISOMENTHONEC₁₀H₁₈O154.25 Da
(+)-PULEGONEC₁₀H₁₆O152.23 Da
(-)-ALPHA-PINENEC₁₀H₁₆136.23 Da
(-)-LIMONENEC₁₀H₁₆136.23 Da
(-)-MENTHONEC₁₀H₁₈O154.25 Da
1,8-CINEOLEC₁₀H₁₈O154.25 Da
1-METHYL-CYCLOHEXAN-3-ONE
1-OCTEN-3-OLC₈H₁₆O128.21 Da
3-OCTANOLC₈H₁₈O130.23 Da
3-OCTYL-ACETATEC₁₀H₂₀O₂172.26 Da
ACETIC-ACIDC₂H₄O₂60.05 Da
ALPHA-HUMULENEC₁₅H₂₄204.35 Da
ALPHA-PINENEC₁₀H₁₆136.23 Da
BETA-PINENEC₁₀H₁₆136.23 Da
BUTYRIC-ACIDC₄H₈O₂88.11 Da
CARVONEC₁₀H₁₄O150.22 Da
CARYOPHYLLENEC₁₅H₂₄204.35 Da
CINEOLC₁₀H₁₈O154.25 Da
DECYLIC-ACIDC₁₀H₂₀O₂172.26 Da
DIOSMINC₂₈H₃₂O₁₅608.5 Da
DIPENTENEC₁₀H₁₆136.23 Da
FORMIC-ACIDCH₂O₂46.025 Da
GERANIOLC₁₀H₁₈O154.25 Da
GERMACRENE-DC₁₅H₂₄204.35 Da
ISOHEPTYLIC-ACID
ISOMENTHONEC₁₀H₁₈O154.25 Da
ISONEOMENTHOLC₁₀H₂₀O156.26 Da
JASMONEC₁₁H₁₆O164.24 Da
LIMONENEC₁₀H₁₆136.23 Da
LIMONENE-ACETATE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources