Gymnema

Also known as: Miracle Fruit

Botanical Overview

Gymnema (Gymnema sylvestre) is a flowering plant in the Asclepiadaceae family. This plant has earned a place in traditional medicine through its consistent therapeutic benefits, recorded across multiple cultures. This species belongs to the Asclepiadaceae family, a group of flowering plants.

General Description

It has been used in Ayurvedic medicine. Common names include gymnema, Australian cowplant, and Periploca of the woods, and the Hindi term gurmar Tamil(சிறுகுறிஞ்சான்) Sirukurunjan, which means “sugar destroyer” The leaves and extracts contain gymnemic acids, the major bioactive constituents that interact with taste receptors on the tongue to temporarily suppress the taste of sweetness.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Asclepiadaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Gymnema has been recorded in 10 countries and territories worldwide, including Burkina Faso, Benin, Cameroon, China, Ghana, and others.

Traditional Uses

Gymnema has been traditionally used for digestive health, respiratory conditions, and urinary tract health, among other applications.

Digestive health.

  • Laxative
  • Stomachic

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Cough

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Urinary tract health.

  • Diuretic

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
  • Saponin: soap-like compounds with immune-modulating activity
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Burkina Faso, Benin, Cameroon, China, Ghana, India, Nigeria, Senegal, Togo, Taiwan.

Complete Use Records

CategoryCultural Context
Bite(Snake)Sudan
DiabetesIndia
ErrhineIndia
EyeIndia
FurunculosisIndia
ParageusiaIndia
StimulantIndia
TongueElsewhere
UterotonicIndia
CardiotonicIndia
CoughIndia
DiureticIndia
LaxativeIndia
StomachicIndia
BiliousIndia

Complete Chemical Inventory

CompoundFormulaMW
(-)-VIBURNITOLC₆H₁₂O₅164.16 Da
ASCORBIC-ACIDC₆H₈O₆176.12 Da
ASH
BETA-CAROTENEC₄₀H₅₆536.9 Da
BETAINEC₅H₁₁NO₂117.15 Da
CALCIUMCa40.08 Da
CHOLINEC₅H₁₄NO+104.17 Da
CHROMIUMCr51.996 Da
COBALTCo58.93319 Da
CONDURITOL-AC₆H₁₀O₄146.14 Da
FATC₁₆H₃₂O₂256.42 Da
FIBER(CRUDE)
FIBER(DIETARY)
GURMARIN
GYMNEMAGENINC₃₀H₅₀O₆506.7 Da
GYMNEMASAPONIN-I
GYMNEMASAPONIN-II
GYMNEMASAPONIN-III
GYMNEMASAPONIN-IV
GYMNEMASAPONIN-VC₅₄H₉₀O₂₄1123.3 Da
GYMNEMASIDE-I
GYMNEMASIDE-II
GYMNEMASIDE-III
GYMNEMASIDE-IV
GYMNEMASIDE-V
GYMNEMASIDE-VIC₄₂H₇₂O₁₄801.0 Da
GYMNEMASIDE-VII
GYMNEMASIN-A
GYMNEMASIN-B
GYMNEMASIN-C

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources