Botanical Overview
Guaiac (Guaiacum sp.) is a species in the Zygophyllaceae family. This species belongs to the Zygophyllaceae family, a group of flowering plants. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 25 compounds in this species, suggesting potential medicinal value.

Family Context
The Zygophyllaceae family is widely distributed. Notable medicinal members include:
- Puncture-vine — 45 documented uses
- Harmel — 40 documented uses
- Chaparral — 18 documented uses
- Fagonia cretica — 15 documented uses
Active Compounds
Phytochemical research has identified 25 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Tannin: astringent compounds that tighten tissues and resist infection
- Saponin: soap-like compounds with immune-modulating activity
Research Status
Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Additional phytochemical investigation could identify novel bioactive compounds in this plant.