Guaiac

Botanical Overview

Guaiac (Guaiacum sp.) is a species in the Zygophyllaceae family. This species belongs to the Zygophyllaceae family, a group of flowering plants. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 25 compounds in this species, suggesting potential medicinal value.

Family Context

The Zygophyllaceae family is widely distributed. Notable medicinal members include:

Active Compounds

Phytochemical research has identified 25 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Tannin: astringent compounds that tighten tissues and resist infection
  • Saponin: soap-like compounds with immune-modulating activity

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Additional phytochemical investigation could identify novel bioactive compounds in this plant.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Complete Chemical Inventory

CompoundFormulaMW
(-)-HYDROGUAIARETIC-ACID
24-O-BETA-D-GLUCOPYRANOSYLOFFICIGENIN
3BETA,20-DIHYDROXY-30-NOROLEAN-12-EN-28-OIC-ACID
BIS-METHYLENEQUINONE
CRESOL
FUROGUAIACIDIN
FUROGUAIACINC₂₀H₂₀O₅340.4 Da
FUROGUAIAOXCIDIN
GUAIACENE
GUAIACOLC₇H₈O₂124.14 Da
GUAIACONIC-ACID
GUAIAGUTIN
GUAIARETIC-ACIDC₂₀H₂₄O₄328.4 Da
GUAIASAPONIN
GUAIAZULENEC₁₅H₁₈198.30 Da
GUAIENEC₁₅H₂₄204.35 Da
GUAIGUTTIN
GUAIOLC₁₅H₂₆O222.37 Da
GUAIOXIDEC₁₅H₂₆O222.37 Da
MESO-DIHYDROGUAIARETIC-ACIDC₂₀H₂₆O₄330.4 Da
OFFICIGENINC₆₀H₉₂O₉957.4 Da
RESINC₁₅H₂₄204.35 Da
SAPONINC₅₈H₉₄O₂₇1223.3 Da
TANNIN
VANILLINC₈H₈O₃152.15 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources