Honey Locust

Botanical Overview

Honey Locust (Gleditsia triacanthos) belongs to the Fabaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The legume family (Fabaceae) includes trees, shrubs, and herbs that produce pods (legumes) and form nitrogen-fixing root nodules through symbiosis with bacteria. The flowers are typically pea-shaped with five petals. This large family provides food staples, timber, and numerous medicinal species.

General Description

Honey locust trees are highly adaptable to different environments, and the species has been introduced worldwide. Outside its natural range it can be an aggressive, damaging invasive species.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Fabaceae family is large and globally distributed. Notable medicinal members include:

Geographic Distribution

Honey Locust has been recorded in 10 countries and territories worldwide, including Australia, Canada, Germany, Spain, France, and others.

Traditional Uses

Honey Locust has been traditionally used for pain and inflammation and nervous system disorders.

Pain and inflammation.

  • Anodyne

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Nervous system disorders.

  • Narcotic

Nervous system support involves taking the herb as a warm tea, often in the evening or before bed. The calming compounds interact with neurotransmitter systems to promote relaxation and restful sleep.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Phenolic: antioxidant compounds that neutralize free radicals
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Narcotic. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Australia, Canada, Germany, Spain, France, Italy, Portugal, Romania, Ukraine, United States.

Complete Use Records

CategoryCultural Context
AnodynePortuguese
CoffeeLesotho
FodderLesotho
FruitLesotho
MydriaticFrench
NarcoticSpanish
OxytoxicElsewhere

Complete Chemical Inventory

CompoundFormulaMW
(+)-CATECHINC₁₅H₁₄O₆290.27 Da
(-)-EPICATECHIN-3-GLUCOSIDE
5-(3,4-DIHYDROXYCINNAMOYL)-(-)-QUINIC-ACID
7,3',4',5'-TETRAHYDROXYISOFLAVANOL
ACETIC-ACIDC₂H₄O₂60.05 Da
ACRAMMERIN
ALKALOID
ASH
CALCIUMCa40.08 Da
CARBOHYDRATES
DIHYDROXY-4-METHOXY-ISOFLAVONE
DIHYDROXYSTEARIC-ACIDC₁₈H₃₆O₄316.5 Da
EPICATECHOL-3-D-GLUCOSIDE-DIHYDRIATE
FATC₁₆H₃₂O₂256.42 Da
FIBER
FISETINC₁₅H₁₀O₆286.24 Da
FUSTINC₁₅H₁₂O₆288.25 Da
GALACTOSEC₆H₁₂O₆180.16 Da
GLEDITSCHIOSIDES
GLUCOSEC₆H₁₂O₆180.16 Da
GLUCURONIC-ACIDC₆H₁₀O₇194.14 Da
HYPOXYSIN
LEUCOCYANIDINC₁₅H₁₄O₇306.27 Da
MANNOGALACTAN
MANNOSEC₆H₁₂O₆180.16 Da
N-METHYL-BETA-PHENYLETHYLAMINEC₉H₁₃N135.21 Da
OLMELINC₁₆H₁₂O₅284.26 Da
PHLOBAPHENE
PHOSPHORUSP30.97376200 Da
PROTEIN

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources