Downy Hemp Nettle

Botanical Overview

Downy Hemp Nettle (Galeopsis segetum) is a species in the Lamiaceae family. The mint family (Lamiaceae) includes aromatic herbs and shrubs with square stems, opposite leaves, and two-lipped flowers. Many species produce essential oils in glandular trichomes on their leaves and stems. This family is one of the most important sources of culinary and medicinal herbs worldwide. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 10 compounds in this species, suggesting potential medicinal value.

General Description

It grows as a weed in arable ground throughout Europe. Although superficially resembling the stinging nettle it is of a different family and does not sting.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Lamiaceae family is large and widely distributed. Notable medicinal members include:

  • Basil — 86 documented uses
  • Rosemary — 60 documented uses
  • Agbo — 54 documented uses
  • Sage — 49 documented uses

Geographic Distribution

Downy Hemp Nettle has been recorded in 10 countries and territories worldwide, including Belgium, Switzerland, Germany, Denmark, Spain, and others.

Active Compounds

Phytochemical research has identified 10 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Tannin: astringent compounds that tighten tissues and resist infection

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Belgium, Switzerland, Germany, Denmark, Spain, France, United Kingdom, Luxembourg, Netherlands, Unknown.

Complete Chemical Inventory

CompoundFormulaMW
8-HYDROXYFLAVONES
8-O-ACETYLHARPAGIDEC₁₇H₂₆O₁₁406.4 Da
ANTIRRHINOSIDEC₁₅H₂₂O₁₀362.33 Da
ANTIRRHINOSIDE-5-O-GLUCOSIDE
FLAVONOIDS
HARPAGIDEC₁₅H₂₄O₁₀364.34 Da
HYPOLAETIN-4'-METHYL ETHER-7-(2'-ALLOSYL)-GLUCOSIDE
IRIDOIDSC₂₀H₂₄O₁₂456.4 Da
SILICAO₂Si60.084 Da
TANNINS

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources