Japanese Knotweed

Also known as: Giant Knotweed, Mexican Bamboo, Hu-Zhang

Botanical Overview

Japanese Knotweed (Fallopia japonica) is a species in the Polygonaceae family. The buckwheat family (Polygonaceae) includes herbs, shrubs, and vines with swollen stem nodes (joints) and simple, alternate leaves with sheathing stipules called ochreae. The flowers are small and clustered. Many species contain anthraquinone glycosides and tannins. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 30 compounds in this species, suggesting potential medicinal value.

General Description

Common names include Japanese knotweed and Asian knotweed. It is native to East Asia in Japan, China and Korea. In North America and Europe, the species has successfully established itself in numerous habitats; it is classified as a pest and invasive species in several countries. The plant is popular with beekeepers and its young stems are edible, making it an increasingly popular foraged vegetable with a flavour described as lemony rhubarb.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Polygonaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Japanese Knotweed has been recorded in 10 countries and territories worldwide, including Austria, Belgium, Germany, France, Ireland, and others.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Phenolic: antioxidant compounds that neutralize free radicals
  • Coumarin: aromatic compounds with anticoagulant and anti-inflammatory effects

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Austria, Belgium, Germany, France, Ireland, South Korea, Luxembourg, Netherlands, Slovakia, United States.

Complete Chemical Inventory

CompoundFormulaMW
(+)-CATECHINC₁₅H₁₄O₆290.27 Da
2,5-DIMETHYL-7-HYDROXYCHROMONEC₁₁H₁₀O₃190.19 Da
2,5-DIMETHYL-7-HYDROXYCHROMONE-7-MONOACETATE
2-METHOXY-6-ACETYL-7-METHYL-JUGLONE
2-METHOXY-6-ACETYL-7-METHYL-JUGLONE-MONOACETATE
7-HYDROXY-4-METHOXY-5-METHYLCOUMARINC₁₁H₁₀O₄206.19 Da
7-HYDROXY-4-METHOXY-5-METHYLCOUMARIN-8-MONOACETATE
ANTHRAQUINONESC₁₄H₈O₂208.21 Da
ARSENICAs74.92159 Da
BARIUMBa137.33 Da
BROMINEBr₂159.81 Da
CALCIUMCa40.08 Da
CHLORINECl₂70.90 Da
CHROMIUMCr51.996 Da
CHRYSOPHANOLC₁₅H₁₀O₄254.24 Da
CITREOROSEINC₁₅H₁₀O₆286.24 Da
COPPERCu63.55 Da
EMODINC₁₅H₁₀O₅270.24 Da
EMODIN-8-BETA-D-GLUCOSIDEC₂₁H₂₀O₁₀432.4 Da
EMODIN-8-GLUCOSIDEC₂₁H₂₀O₁₀432.4 Da
FALLACINOLC₁₆H₁₂O₆300.26 Da
IODINEI₂253.8089 Da
IRONFe55.84 Da
ISOQUERCITRINC₂₁H₂₀O₁₂464.4 Da
LEADPb207 Da
MANGANESEMn54.93804 Da
MOLYBDENUMMo95.95 Da
NICKELNi58.693 Da
PHOSPHORUSP30.97376200 Da
PHYSCION-8-BETA-D-GLUCOSIDEC₂₂H₂₂O₁₀446.4 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources