Erythroxylum zambesiacum

Botanical Overview

Erythroxylum zambesiacum is a species in the Erythroxylaceae family. The coca family (Erythroxylaceae) includes tropical shrubs and small trees with alternate leaves and small flowers. The plants produce alkaloids concentrated in the leaves, most notably cocaine and related tropane alkaloids. Species in this family have a long history of traditional stimulant and medicinal use in South America. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 13 compounds in this species, suggesting potential medicinal value.

Family Context

The Erythroxylaceae family is primarily neotropical. Notable medicinal members include:

Geographic Distribution

Erythroxylum zambesiacum has been recorded in 7 countries and territories worldwide, including Botswana, Congo (DRC), Congo, Mozambique, Namibia, and others.

Active Compounds

Phytochemical research has identified 13 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. The limited documentation available for this species represents an opportunity for ethnobotanical research.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Botswana, Congo (DRC), Congo, Mozambique, Namibia, Zambia, Zimbabwe.

Complete Chemical Inventory

CompoundFormulaMW
(+)-6BETA-BENZOYLOXYTROPAN-3ALPHA,7BETA-OL
(+)-6BETA-BENZOYLOXYTROPAN-3ALPHA-OL
3,4,5-TRIMETHOXYBENZOIC-ACIDC₁₀H₁₂O₅212.20 Da
3,4,5-TRIMETHOXYCINNAMATEC₁₂H₁₃O₅-237.23 Da
3ALPHA-(3,4,5-TRIMETHOXYBENZOYLOXY)NORTROPANE-6BETA-OL
3ALPHA-(3,4,5-TRIMETHOXYBENZOYLOXY)TROPAN-6-BETA,7,BETA-DIOL
3ALPHA-PHENYLACETOXYTROPAN-6BETA-OLC₁₆H₂₁NO₃275.34 Da
6BETA-BENZOYLOXY-3ALPHA-(3,4,5-TRIMETHOXYCINNAMOYLOXY)TROPANE
6BETA-BENZOYLOXY-3ALPHA-(3,4,5-TRIMETHOXYCINNAMOYLOXY)TROPANE-7BETA-OL
7BETA-ACETOXY-6BETA-BENZOYLOXY-3ALPHA-(3,4,5-TRIMETHOXYCINNAMOYLOXY)TROPANE
ACETIC-ACIDC₂H₄O₂60.05 Da
ALKALOIDS
PHENYLACETIC-ACIDC₈H₈O₂136.15 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources