Amazonian Coca

Also known as: Ipadu

Botanical Overview

Amazonian Coca (Erythroxylum coca var. ipadu) is a flowering plant in the Erythroxylaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The coca family (Erythroxylaceae) includes tropical shrubs and small trees with alternate leaves and small flowers. The plants produce alkaloids concentrated in the leaves, most notably cocaine and related tropane alkaloids. Species in this family have a long history of traditional stimulant and medicinal use in South America.

Family Context

The Erythroxylaceae family is primarily neotropical. Notable medicinal members include:

Geographic Distribution

Amazonian Coca has been recorded in 7 countries and territories worldwide, including Benin, Brazil, Colombia, Guatemala, Peru, and others.

Traditional Uses

Amazonian Coca has been traditionally used for digestive health, respiratory conditions, and urinary tract health, among other applications.

Digestive health.

  • Carminative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Asthma

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Urinary tract health.

  • Diuretic
  • Edema

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Active Compounds

Phytochemical research has identified 13 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Narcotic, Poison. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Benin, Brazil, Colombia, Guatemala, Peru, United States, Unknown.

Complete Use Records

CategoryCultural Context
MasticatoryAmerindian, Colombia(Cubeo), Elsewhere, India
NarcoticColombia(Cubeo), Ecuador, Elsewhere, Turkey
StimulantElsewhere, India, Peru, Turkey
AnestheticElsewhere, Europe, India
HungerAmerindian, Brazil(Maku), Colombia(Cubeo)
AsthmaAmerindian, Europe
HallucinogenEcuador(Jivaro), Peru
RheumatismAmerindian, Europe
AperientAmerindian
AstringentIndia
CarminativeAmerindian
DepressionEurope
DepurativeElsewhere
DigestiveAmerindian
DiureticAmerindian
EdemaAmerindian
EpistaxisAmerindian
FractureAmerindian
HoarsenessAmerindian
LongevityAmerindian
MydriaticIndia
NervousnessEurope
NeurastheniaEurope
NeuritisIndia
PoisonSouth America
PsychedelicAmerindian
SpleenAmerindian
ThirstAmerindian
ThroatEurope
Ache(Head)Amerindian

Complete Chemical Inventory

CompoundFormulaMW
COCAINEC₁₇H₂₁NO₄303.35 Da
KAEMPFEROL-3-O-ARABINOSIDEC₂₀H₁₈O₁₀418.3 Da
KAEMPFEROL-3-O-GALACTOSYLXYLOSIDE
KAEMPFEROL-3-O-GLUCOSIDEC₂₁H₂₀O₁₁448.4 Da
KAEMPFEROL-3-O-GLUCOSYLXYLOSIDE
KAEMPFEROL-3-O-XYLOSYLGALACTOSIDE
KAEMPFEROL-3-O-XYLOSYLGLUCOSIDE
QUERCETIN-3-O-ARABINOSIDEC₂₀H₁₈O₁₁434.3 Da
QUERCETIN-3-O-GLUCOSIDEC₂₁H₂₀O₁₂464.4 Da
QUERCETIN-3-O-GLUCOSYLGALACTOSIDE
QUERCETIN-3-O-GLUCOSYLXYLOSIDE
QUERCETIN-3-O-XYLOSYLGALACTOSIDE
QUERCETIN-3-O-XYLOSYLGLUCOSIDE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources