Eleuthero Ginseng

Also known as: Siberian Ginseng, Spiny Ginseng, Wu jia, Ci wu jia (Pinyin)

Botanical Overview

Eleuthero Ginseng (Eleutherococcus senticosus) is a species in the Araliaceae family. The ivy family (Araliaceae) includes trees, shrubs, and climbers with alternate, often compound leaves and small flowers arranged in umbels. The fruits are typically fleshy berries. Many species produce triterpenoid saponins with adaptogenic and anti-inflammatory properties. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 30 compounds in this species, suggesting potential medicinal value.

General Description

It is native to Northeastern Asia. It may be colloquially called devil’s bush, Siberian ginseng, taiga root, eleuthero, ciwujia, Devil’s shrub, shigoka, touch-me-not, wild pepper, or kan jang. E. senticosus has a history of use in folklore and traditional Chinese medicine. Root extracts of E. senticosus are sold as a dietary supplement or cosmetic, usually under the name Siberian ginseng.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Araliaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Eleuthero Ginseng has been recorded in 10 countries and territories worldwide, including China, Japan, North Korea, South Korea, Norway, and others.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Further ethnobotanical and pharmacological research may reveal additional therapeutic applications for this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: China, Japan, North Korea, South Korea, Norway, Russia, Taiwan, Ukraine, United States, Unknown.

Complete Chemical Inventory

CompoundFormulaMW
(+)-LIRIODENDRINC₃₄H₄₆O₁₈742.7 Da
(+)-MEDIORESINOL-DI-O-BETA-D-GLUCOSIDE
(+)-PINORESINOL-DI-O-BETA-D-GLUCOSIDE
(+)-PINORESINOL-O-BETA-D-GLUCOSIDE
(+)-SYRINGARESINOL-O-BETA-D-GLUCOSIDE
(-)-SESAMINC₂₀H₁₈O₆354.4 Da
1,5-DI-O-CAFFEOYLQUINIC-ACID
2,6-DIMETHOXY-P-BENZOQUINONEC₈H₈O₄168.15 Da
3,4-DIHYDROXYBENZOIC-ACIDC₁₄H₁₂O₈308.24 Da
3-O-ALPHA-L-RHAMNOPYRANOSYL-(1,2)-ALPHA-ARABINOPYRANOSYL-OLEANOLIC-ACID
ACANTHOSIDE-DC₃₄H₄₆O₁₈742.7 Da
ALPHA-GLUCOSEC₆H₁₂O₆180.16 Da
ALPHA-MALTOSEC₁₂H₂₂O₁₁342.30 Da
ALPHA-TOCOPHEROLC₂₉H₅₀O₂430.7 Da
AMYGDALINC₂₀H₂₇NO₁₁457.4 Da
ARIENSIN
ASCORBIC-ACIDC₆H₈O₆176.12 Da
ASH
BETA-CALYCANTHOSIDE
BETA-CAROTENEC₄₀H₅₆536.9 Da
BETA-GLUCOSEC₆H₁₂O₆180.16 Da
BETA-HEDERINC₄₁H₆₆O₁₁735.0 Da
BETA-MALTOSEC₁₂H₂₂O₁₁342.30 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
BETULINIC-ACIDC₃₀H₄₈O₃456.7 Da
CAFFEIC-ACIDC₉H₈O₄180.16 Da
CAFFEIC-ACID-ETHYL-ESTERC₁₁H₁₂O₄208.21 Da
CALCIUMCa40.08 Da
CAROTENEC₄₀H₅₆536.9 Da
CHLOROGENIC-ACIDC₁₆H₁₈O₉354.31 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources