Thorn Apple

Botanical Overview

Thorn Apple (Datura innoxia) is a flowering plant in the Solanaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The nightshade family (Solanaceae) includes herbs, shrubs, and small trees with alternate leaves and star-shaped or trumpet-shaped flowers. The fruits are typically berries or capsules. Many species produce potent alkaloids including tropanes, solanines, and nicotine, making this family both medicinally valuable and potentially toxic.

General Description

It is more rarely called sacred datura, a common name which is applied more often to the closely related Datura wrightii. It is native to the Southwestern United States, Central and South America, and introduced in Africa, Asia, Australia and Europe. The scientific name is often cited as D. innoxia. When English botanist Philip Miller first described the species in 1768, he misspelled the Latin word innoxia (inoffensive) when naming it D. inoxia. The name Datura meteloides was for some time erroneously applied to some members of the species, but that name has now been abandoned.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Solanaceae family is widely distributed worldwide. Notable medicinal members include:

Geographic Distribution

Thorn Apple has been recorded in 10 countries and territories worldwide, including Australia, Spain, Israel, India, Mexico, and others.

Traditional Uses

Thorn Apple has been traditionally used for respiratory conditions, skin and wound care, and nervous system disorders, among other applications.

Respiratory conditions.

  • Asthma
  • Expectorant

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Sore

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Nervous system disorders.

  • Sedative
  • Spasm

Nervous system support involves taking the herb as a warm tea, often in the evening or before bed. The calming compounds interact with neurotransmitter systems to promote relaxation and restful sleep.

Active Compounds

Phytochemical research has identified 20 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Australia, Spain, Israel, India, Mexico, Namibia, Pakistan, Saudi Arabia, Sweden, United States.

Complete Use Records

CategoryCultural Context
SedativeIndia, Nepal
TumorIndia, Pakistan
Ache(Ear)India
AnestheticIndia
AsthmaNepal
DemulcentIndia
ExpectorantIndia
Motion-SicknessIndia
OphthalmiaIndia
ParkinsonianismIndia
PhthisisIndia
PilesIndia
SeasicknessIndia
SoreIndia
SpasmIndia

Complete Chemical Inventory

CompoundFormulaMW
(-)-3ALPHA,6BETA-DITIGLOYLOXYTROPANEC₁₈H₂₇NO₄321.4 Da
7-HYDROXY-3,6-DITIGLOYLOXYTROPANEC₁₈H₂₇NO₅337.4 Da
ALKALOIDS
APOATROPINEC₁₇H₂₁NO₂271.35 Da
ATROPINEC₁₇H₂₃NO₃289.4 Da
BETULINIC-ACIDC₃₀H₄₈O₃456.7 Da
CUSCOHYGRINE
DATURADIOLC₃₀H₅₀O₂442.7 Da
DATURANOLONE
DITIGLOYLTELOIDINEC₁₈H₂₇NO₅337.4 Da
FATC₁₆H₃₂O₂256.42 Da
HYOSCYAMINEC₁₇H₂₃NO₃289.4 Da
METELOIDINEC₁₃H₂₁NO₄255.31 Da
NORHYOSCYAMINEC₁₆H₂₁NO₃275.34 Da
PROTEIN
PSEUDOTROPINEC₈H₁₅NO141.21 Da
SCOPOLAMINEC₁₇H₂₁NO₄303.35 Da
SCOPOLETINC₁₀H₈O₄192.17 Da
TIGLOIDINEC₁₃H₂₁NO₂223.31 Da
TROPINEC₈H₁₅NO141.21 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources