Buffalo Gourd

Botanical Overview

Buffalo Gourd (Cucurbita foetidissima) belongs to the Cucurbitaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The gourd family (Cucurbitaceae) includes climbing or trailing vines with tendrils, large alternate leaves, and showy yellow or white flowers that are typically unisexual. The fruits are fleshy gourds, melons, or squashes with many seeds. Many species produce cucurbitacins, bitter compounds with purgative and anti-inflammatory activity.

General Description

It has numerous common names, but is most commonly called the buffalo gourd in English. The type specimen was collected from Mexico by Alexander von Humboldt and Aimé Bonpland sometime before 1817. In Latin, foetidissima means most unpleasant smell. The buffalo gourd has evolved in the semiarid regions and is well-adapted to desert environments. It contains high amounts of protein and carbohydrates and yields abundant oil. The carbohydrates that are formed in the tap root have led to the idea of growing the plant for biofuel. The fruit is consumed by both humans and animals. When mature, a stage marked by increasing desiccation of vine, leaves, fruit-stem, and fruit, the fruit begins its final gourd stage. Geographic location and genetics make it highly likely that Cucurbita scabridifolia originated as a naturally occurring hybrid of C. foetidissima and Cucurbita pedatifolia.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Cucurbitaceae family is widely distributed in tropical and subtropical regions. Notable medicinal members include:

Geographic Distribution

Buffalo Gourd has been recorded in 10 countries and territories worldwide, including Afghanistan, Australia, Belgium, Brazil, Switzerland, and others.

Traditional Uses

Buffalo Gourd has been traditionally used for digestive health.

Digestive health.

  • Laxative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Terpene: aromatic compounds with anti-inflammatory and antimicrobial properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Afghanistan, Australia, Belgium, Brazil, Switzerland, China, Germany, Mexico, United States, Unknown.

Complete Use Records

CategoryCultural Context
LaxativeUS(Tewa)
SoapElsewhere

Complete Chemical Inventory

CompoundFormulaMW
ALANINEC₃H₇NO₂89.09 Da
AMYLOSE
ARGININEC₆H₁₄N₄O₂174.20 Da
ASH
ASPARTIC-ACIDC₄H₇NO₄133.10 Da
CALCIUMCa40.08 Da
CARBOHYDRATES
CUCURBITACIN-BC₃₂H₄₆O₈558.7 Da
CUCURBITACIN-DC₃₀H₄₄O₇516.7 Da
CUCURBITACIN-EC₃₂H₄₄O₈556.7 Da
CYSTEINEC₃H₇NO₂S121.16 Da
FATC₁₆H₃₂O₂256.42 Da
FIBER
FOETIDISSIMOSIDE-A
GLUCOSEC₆H₁₂O₆180.16 Da
GLUTAMIC-ACIDC₅H₉NO₄147.13 Da
GLYCINEC₂H₅NO₂75.07 Da
HEMICELLULOSE
HISTIDINEC₆H₉N₃O₂155.15 Da
ISOCUCURBITACIN-BC₃₂H₄₆O₈558.7 Da
ISOLEUCINEC₆H₁₃NO₂131.17 Da
LEUCINEC₆H₁₃NO₂131.17 Da
LINOLEIC-ACIDC₁₈H₃₂O₂280.4 Da
LINOLENIC-ACIDC₁₈H₃₀O₂278.4 Da
LYSINEC₆H₁₄N₂O₂146.19 Da
METHIONINEC₅H₁₁NO₂S149.21 Da
MYRISTIC-ACIDC₁₄H₂₈O₂228.37 Da
OLEIC-ACIDC₁₈H₃₄O₂282.5 Da
PALMITIC-ACIDC₁₆H₃₂O₂256.42 Da
PHENYLALANINEC₉H₁₁NO₂165.19 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources